José Enrique Alés MartínezHospital Nuestra Señora de Sonsoles, Ávila, Spain

Dr. Alés is currently Head of the Oncology Unit at Hospital Nuestra Señora de Sonsoles in Ávila, Spain. After his clinical training in Hospital Puerta de Hierro in Madrid, he was a Wilmot Fellow at Strong Memorial Cancer Center, Rochester, NY, where he worked on cellular activation mechanisms and apoptosis in tumor models, research that continued at the Center for Molecular Biology in Madrid, Spain. In the following years he held clinical research positions in medical departments of pharmaceutical laboratories, being responsible for the design and final analysis of clinical trials in breast, lung and colorectal cancer. Later on Dr. Alés took on responsibilities as clinical researcher and director of the Clinical Research Program in Hospital Ruber Internacional in Madrid. Dr. Alés has been principal investigator or co-investigator in over 120 clinical trials and published original basic and clinical research articles in peer-reviewed journal, review articles and book chapters. He has served in the Steering Committee of the MAP.3 trial on breast cancer chemoprevention. Dr. Alés is also a member of the Spanish Group of Investigation in Breast Cancer (GEICAM), ASCO, ESMO, Ethics Committees and other scientific associations. Among his main clinical and research interests are the pharmacologic prevention of breast cancer, the manipulation of the immune system for cancer treatment and prevention and the use of imaging to predict and analyze the response to cancer treatments.