Psych 10 Holyoak Lec

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    Psychology 10: Holyoak 9/22/11

    What is Psychology? How did it arise?

    Psychology: The scientific study of the causes of thoughts, feelings,

    and behavior.

    o Uses the scientific method to find causes

    o Why the interest in causes?

    Why do people do what they do (good, bad, or weird)?

    If we know causes, we can change behavior

    Treatment

    Therapy

    Causes: Levels of explanation

    o Genetic mechanism: behavior genetics

    o Neural mechanism: neuroscience

    o

    Behavioral processes: learning, cognitive

    , developmental , social

    o Evolutionary function: comparative , evolutionary

    o Each level has different ways of explaining the nature of

    something.

    E.g. Observation: I want to go to In-n-Out. What caused that

    behavior?

    o How long has it been since I ate? (Learning)

    o Stomach Load/Hormonal Signals (Neuroscience) Temporary

    o I want to talk to friends (Social) Influences

    o Im a human not a termite (Behavior genetics, comparative)

    o Eating gives us energy to reproduce (evolutionary)

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    o Im too old for a bottle and too young for gourmet food

    (developmental) PI

    o I ate at In-n-Out in the past and it was good (learning,

    cognitive)

    o When I ate at In-n-Out in the past, my brain releaseddopamine (neuroscience)

    o I ate McDonalds in the past and got ill (learning)

    Three kinds of influences:

    o Temporary: brain and glands respond to current state

    (Motivation, Emotion, & Mood)

    o Permanent/Persistent: experience changes behavior, brain

    responds differently (Learning & Memory)

    o Heredity: gene expression (Genes: DNA)

    E.g. When a experiencing a trauma:

    o Short-term changes in behavior: Changes in hormonal

    responses, brain chemistry, environmental cues, genetic

    make-up

    o Learning/Memory Formation, Gene Expression

    o Which both can lead to long-term changes in behavior: Bad

    memories, inability to deal with new stress

    o Which can ultimately lead to Post-traumatic stress disorder

    (PTSD)o From there: Clinical

    Methods of Psychology

    Opinion

    o Nonscientific view

    o Not based on observation

    o Not systematic

    o Two conflicting opinions can be valid

    Fact

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    o Verifiable

    o Two people can agree that a certain event happened a certain

    way

    o Can get blurred but in science must make sure that facts are

    recorded the way they areo One bit of information

    o One objective observation

    Hypothesis

    o Based on what is observed

    o Leads to prediction

    o Can be changed

    o A testable idea or proposal (leads to a prediction about a fact)

    o E.g. the chicken and the egg theory

    Theory

    o Gives explanation

    o Generates more hypothesis

    o Leads to new facts

    o A set of interrelated assumptions

    o Organizes a set of facts giving them a common explanation

    o Generates hypotheses and predicts new facts

    o Judged by their usefulness, generality, and parsimony

    o E.g. simple theory explains a lot Example:

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    o Bad vs. Good driver

    Find the correlation (relationship) between drivers who

    talk and non talking

    While the data may show that good drivers are usually

    those who do not talk on the phone it does not meanthat is the case for everyone. More info is needed.

    o Experiment

    Independent variable

    Avoid confounds

    To make sure that it does not prefer one group

    over the other.

    Dependent variable

    Objective

    Reliable

    Valid make a reasonable inference

    Selection of subjects/participants

    Random (representative sample)

    Although it may seem that random is

    unorganized, it is to make sure that the sample

    group is representative of all group types.

    o Theory

    Complex activities require attention (cant attend toeverything at once)

    Attention is limited

    Divided attention (less focus) compromises performance

    Psychologists have found that memory encoding is

    especially compromised by multitasking (multitasking

    have consequences)

    How did Psychology get to where it is now?

    Everyone thinks they are psychologists that they know the causes

    of their behavior.

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    o Intuitive approach (not scientific method)

    o We do what we do according to our own free will. (We decide

    what to do based on reflecting on past performances).

    o Dualism: mind and body separate and independent. (We

    think we are our consciousness.) Rationalism: We do what we do base on our ability to reason.

    (Based on free will)

    Instinct: We do things because thats how we are. (natural

    born this way :P)

    Humans vs. Animals?

    o Social, physical, mental, religious views of how we are

    different

    o Challenges:

    Behavioral and neural evidence

    Darwins theory

    Philosophical roots (and routes to) Psychology

    Rene Descartes

    o A duelist

    o Theres the mind and the body are in parallel but still

    separate parts

    o Thought animals are completely different.

    o Thought the pineal gland was the center Pineal gland is what makes jet lag. It can tell when it is

    day or night, which is why Descartes called it the third

    eye. It also produces melatonin.

    o Led to the 1st experiment to see how the mind and the brain

    could be connected

    John Locke

    o Empiricism

    Tabula Rasa

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    Born as an innocent baby knowing nothing at all

    Gain knowledge through experience and ideas

    James Mill

    o Materialist

    o Mind and matter are oneo Continuity of humans and other humans (said that were just

    like animals)

    o Were just a type of machine

    Physiological roots (and routes to) Psychology

    Rene Descartes

    Luigi Galvani

    o Physiologist

    o Compared neurons/nerves with electricity

    o Experiment w/ frog legs

    His assistant touched the nerve of the frog legs with an

    electrical current, which made the frog leg twitch.

    Johannes Mller

    o Different nerves/pathways (doctrine of specific nerve

    energies)

    o Experiment: pushed at his eye led to the conclusion of

    physical and visual response

    It is not the nerve but it sends current to a certain partof the brain that makes the visualization

    Pierre Flourens

    o Start experimental brain lesions (ablations) on animals

    To investigate localizationism, i.e., whether different

    parts of the brain had different functions

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    Paul Broca

    o How brain injuries create different responses

    What a person can do or cannot do after the injury

    o Brocas Area in the brain speech production

    Hermann von Helmholtzo Theory of color vision

    3 different kinds of cells on certain wavelengths

    The First Psychologist:

    The German Wave

    o Muller and Helmholtz led to Wilhelm Wundt (1879)-

    Heildelberg, Germany

    Structuralism: Psychology = science of immediate

    experience

    Goal: Describe the elements of perceptual experience

    o Max Wertheimer Gestalt Psychology

    A theory of mind and brain positing; the operational

    principle of Gestalt is that the brain is holistic, parallel,

    and analog, with self-organizing tendencies

    o Sigmund Freud

    Unconscious causes of complex actions and personality

    Therapeutic

    Had minimal influence in psychology today Introduced cocaine as a medical treatment

    American Revolution

    o William James (1842- 1910)

    http://en.wikipedia.org/wiki/Holismhttp://en.wikipedia.org/wiki/Holism
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    Wrote Principles of Psychology

    Functionalism: mental life and behavior is an

    adaptation to environment

    Divisions of memory

    Attention Emotion

    Cognitive Psychology

    The Tao of Psychology (Tao: true nature of world/ doctrine/principles

    Structures:

    o Wundt

    o Representation

    o Brain areas

    o Hippocampus

    o Neurons

    Function:

    o James

    o Processes

    o Cognitive operations

    o Memory

    o Activation

    Structures have some function and function have some type of

    structureExamples of Introspective Report

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    Wanted to understand immediate experience

    Apple

    o Cold, crisp, sweet

    Meaning

    o I see meaning as the blue-grey tip of a kind of scoop, whichhas a bit of yellow above it, and which is just digging into a

    dark mass of what appears to be plastic material.

    Titchener (Wundts student), of Cornell Univ.

    Wundt thinks knowledge are basically mental imagery. Every

    thought is closely tied with concrete images; even abstract word

    meaning

    Problems with Introspection

    o Poor agreement between subjects

    o Most mental operations outside awareness

    o Process might change observed operations

    o Inadequacies of language

    Difficulties led to quest for more objective approaches:

    Behaviorism

    Might have the same visual representation but

    different language

    Classical Conditioning Experiment

    Ivan Pavlov (1849-1936)o His laboratory study was with dogs

    More objective

    o Conditioning of dogs

    Before dogs doesnt salivate when bell rings

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    After when bell rings without food, dogs will still salivate

    Association of food with an inanimate object

    o Foundation for behaviorism

    American Behaviorism (1913-1957)

    John Watson (1878-1958)o 1930-published Behaviorism

    o "Give me a dozen healthy infants, well-formed, and my own

    specified world to bring them up in and I'll guarantee to take

    any one at random and train him to become any type of

    specialist I might select--doctor, lawyer, artist, merchant-

    chief, and, yes, even beggarman and thief, regardless of his

    talents, penchants, tendencies, abilities, vocations, and race

    of his ancestors. I am going beyond my facts and I admit it,

    but so have the advocates of the contrary and they have

    been doing it for many thousands of years."

    Think that he can take anyone and make them into

    anything that he wants with training

    BF Skinner (1904-1990)

    o The Behavior of Organism

    o Skinner box is a chamber that contains a bar or key that an

    animal can press or manipulate in order to obtain food or

    water as a type of reinforcement. The Skinner box also had adevice that recorded each response provided by the animal as

    well as the unique schedule of reinforcement that the animal

    was assigned.

    Using the device researchers could carefully study

    behavior in a very controlled environment.

    Could be used to determine which schedule of

    reinforcement led to the highest rate of response in the

    study subjects.

    Cognitive Revolution (1950-60s)

    Noam Chomsky

    o Modern linguistics

    o Critique of Skinner

    Herbert Simon

    o One of the founder of Artificial Intelligence

    http://psychology.about.com/od/behavioralpsychology/a/schedules.htmhttp://psychology.about.com/od/behavioralpsychology/a/schedules.htm
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    o Human problem solving

    Donald Broadbent

    o Limited capacity

    o Human attention

    George Millero Short-term vs. long-term memory

    21st Century Integrating Mind and Brain

    All cognitive processes have a neural basis. Different area of brain

    are active during different cognitive actions. Use different

    techniques of brain imaging to localize areas in brain associated

    with different cognitive functions.

    Mind over body?

    o Placebo effect

    Influence of a substance or procedure due to receiving

    it, even though substance/procedure itself has no effect

    Effect is due to persons belief

    Negative placebo (e.g., voodoo)

    How is this possible?

    If people believe something to work or they have

    something their body will produce the effects as if

    it is actually supposed to happen.

    o How the brain responds when we do things Functional magnetic resonance imaging (fMRI)

    Can use virtual reality to reduce pain

    How do we ever know that someone is conscious?

    The limits of consciousness are hard to define satisfactorily, and

    we can only infer the self-awareness of others by their appearance

    and their acts. - Plum & Posner

    Principle ofrevealed consciousness: Voluntary (i.e., non-

    reflexive) behavior is taken torevealthe presence of

    consciousness.

    Conscious can be revealed because we can do things

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    In other words, since we dont have access to measuring

    consciousness directly, we rely on behavioral indications of

    consciousness, or a principle of revealed consciousness, by which

    the presence of non-reflexive behavior is taken to reveal the

    presence of consciousness

    Assessing consciousness in brain-injury patients

    Detailed patient history (including structural MRI).

    Repeated daily observation ofspontaneous and elicitedbehavior

    using standardized (albeit subjective) assessments:

    o i. Sustained, reproducible, purposeful, or voluntary response

    to visual, auditory, tactile or noxious stimuli

    o ii. Language comprehension or expression.

    o iii. Awareness of self or the environment

    If any evidence is found of i, ii or iii then the patient is diagnosed

    MCS.

    Ifno evidence is found of i, ii and iii then the patient is diagnosed

    VS.

    Imaging Consciousness

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    If we can see the neural signature of imagining playing tennis

    (motor imagery) and imagining walking around the rooms of ones

    home(Spatial imagery), we can turn this into a code for yes and

    no?

    This would allow patients who cannot produce any behavioraloutput to:

    o (1) Prove they are conscious

    o (2) Communicate with their environment.

    While a persons brain is working, they cant response normally.

    E.g. A patient had been diagnosed VS (i.e., unconscious) for 5

    years. Yet by looking into his brain he could (1) show volitional

    behavior, and (2) correctly respond to 5 out of 6 autobiographical

    questions.

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    The Biology of the Mind 29/09/2011 15:37:00

    Cortex

    Is the reality check part of the brain

    Connect senses

    Thinking cap

    Each neuron have a job Neurons make networks among cells

    Neural Communications

    Brain and nervous systems is incredibly complicated

    The individual neurons are small simple things

    o They either turn on or off

    o Based on how they interact with each other

    Neurons either excite or inhibit

    o

    If only: Excite will blow up

    Inhibit shut everything down

    o Must have a balance

    Motor areas voluntary motion and reflexes

    Sensory areas the 5 senses

    Association areas sensory and memory

    Nervous system is electrical

    Basic neural processing is similar in humans and in other animals.

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    Note similarities in the above brain regions between the rat, cat,

    chimpanzee, and humans, which are all engaged in information

    processing. But association areas are larger in humans.

    The bodys information system is built from billions of

    interconnected cells called neurons.Neurons

    A nerve cell, or a neuron, consists of many different parts.

    Parts of a neuron:

    o Cell Body: Life support center of the neuron.

    Keeps it alive

    Most of our energy is used by our brain

    o Dendrites: Branching extensions at the cell body. Receive

    messages from other neurons.

    Receiving ends, connect to the synapses

    o Axon: Long single extension of a neuron, covered with myelin

    [MY-uh-lin] sheath to insulate and speed up messages

    through neurons.

    o Terminal Branches of axon: Branched endings of an axon that

    transmit messages to other neurons.

    Have a threshold (basically all or nothing)

    o Each neuron receives excitatory and inhibitory signals from

    many neurons. When the excitatory signals minus theinhibitory signals exceed a minimum intensity (threshold) the

    neuron fires an action potential.

    Action Potential

    o A neural impulse. A brief electrical charge that travels down

    an axon and is generated by the movement of positively

    charged atoms (ions) in and out of channels in the axons

    membrane.

    o Properties:

    All-or-None Response: A strong stimulus can trigger

    more neurons to fire, and to fire more often, but it does

    not affect the action potentials strength or speed.

    Intensity of an action potential remains the same

    throughout the length of the axon.

    Synapse:

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    o Synapse [SIN-aps] a junction between the axon tip of the

    sending neuron and the dendrite or cell body of the receiving

    neuron. This tiny gap is called the synaptic gap or cleft.

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    Neurotransmitter:

    o Neurotransmitters (chemicals) released from the sending

    neuron travel across the synapse and bind to receptor sites

    on the receiving neuron, thereby influencing it to generate an

    action potential.o One neurotransmitter can influence many different brain

    areas

    o Reuptake:

    Pills such as those for depression slow the reuptake

    Neurotransmitters in the synapse are reabsorbed into

    the sending neurons through the process ofreuptake.

    This process applies the brakes on neurotransmitter

    action.

    How Neurotransmitter Influence Us

    Serotonin pathways are involved with mood regulation.

    Dopamine Pathways

    o Dopamine pathways are involved with diseases such as

    schizophrenia and Parkinsons disease.

    o Contribute to learning and motion

    Lock and Key Mechanisms

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    o Neurotransmitters bind to the receptors of the receiving

    neuron in a key-lock mechanism.

    o Agonists mimics neurotransmitter

    o Antagonists blocks neurotransmitter

    Psychoactive Drugs Agonists mimic transmitter at receptor

    o Domoic acid (contaminated shellfish), nicotine, propofol

    (Michael Jackson)

    Antagonists block the transmitter at receptor

    o botox

    Modulators alter (up or down) the effect of transmitter at its

    receptor

    o alcohol

    Re-uptake Inhibitors increase effect of transmitters

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    Transmitter Function Treatment Illegal Drugs

    Serotonin Sleep, mood Depression w/SSRIs such as

    prozac

    Lysergic aciddiethylamide

    (LSD), ecstasy

    Norepinephrine Blood pressure,

    attention

    hypertension-

    propranolol,ADHD-ritalin

    Apparently not

    Dopamine Movement,pleasure (reward)

    Parkinsons (L-Dopa),

    Schizophrenia(thorazine,

    haldol)

    Cocaine,amphetamine

    Endogenous

    Opioidsendorphin,

    enkephalin

    Regulation of pain Pain control after

    injury or disease(morphine,

    vicodin)

    Heroin

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    Anandamide Regulation of

    neurotransmission

    Nausea from

    chemotherapy,

    inflammatorydiseases

    Marijuana

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    Example drug effect: ecstasy (an amphetamine) -- primarily

    influences serotonin system

    o Acute effects:

    Heightened perceptions

    Reduced appetite Stimulation

    Elevated mood

    o Adverse effects:

    Clouded thinking

    Hyperthermia

    Disturbed behavior

    Jaw clenching

    o Life threatening effects:

    Hyperthermia

    Arrthymias

    Renal failure

    Nervous Systems

    Nervous System: Consists of all the nerve cells. It is the bodys

    speedy, electrochemical communication system.

    Central Nervous System (CNS): the brain and spinal cord.

    o The Brain and Neural Networks:

    Interconnected neurons form networks in the brain.Theses networks are complex and modify with growth

    and experience.

    o The Spinal Cord and Reflexes:

    Reflexes often only include the spinal cord so for

    example a finger is getting burned, the finger will reflex

    back before the info reaches the brain.

    o The Endocrine System:

    The Endocrine System is the bodys slow chemical

    communication system. Communication is carried out

    by hormones synthesized by a set of glands.

    Hormones:

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    Hormones are chemicals synthesized by the

    endocrine glands that are secreted in the

    bloodstream. Hormones affect the brain and many

    other tissues of the body.

    For example, epinephrine (adrenaline)increases heart rate, blood pressure, blood

    sugar, and feelings of excitement during

    emergency situations.

    The Pituitary Gland:

    Is called the master gland. The anterior pituitary

    lobe releases hormones that regulate other

    glands. The posterior lobe regulates water and

    salt balance.

    Peripheral Nervous System (PNS): the sensory and motor neurons

    that connect the central nervous system (CNS) to the rest of the

    body.

    o Somatic Nervous System: The division of the peripheral

    nervous system that controls the bodys skeletal muscles.

    o Autonomic Nervous System: Part of the PNS that controls the

    glands and other muscles.

    Sympathetic Nervous System: Division of the ANS that

    arouses the body, mobilizing its energy in stressfulsituations. (flight or fight)

    Parasympathetic Nervous System: Division of the ANS

    that calms the body, conserving its energy. (rest and

    digest)

    o The Nerves:

    Nerves consist of neural cables containing many

    axons. They are part of the peripheral nervous system

    and connect muscles, glands, and sense organs to the

    central nervous system.

    The Brain

    A brain lesion experimentally destroys brain tissue to study animal

    behaviors after such destruction.

    Techniques to study the brain:

    o Clinical observation:

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    Clinical observations have shed light on a number of

    brain disorders. Alterations in brain morphology due to

    neurological and psychiatric diseases are catalogued.

    o Electroencephalogram (EEG):

    An amplified recording of the electrical waves sweepingacross the brains surface, measured by electrodes

    placed on the scalp.

    o PET Scan:

    PET (positron emission tomography) scan is a visual

    display of brain activity that detects a radioactive form

    of glucose while the brain performs a given task.

    o MRI Scan:

    MRI (magnetic resonance imaging) uses magnetic fields

    related to blood flow to produce computer-generated

    images that distinguish among different types of brain

    tissue. Top images show ventricular enlargement in a

    schizophrenic patient. Bottom image shows brain

    regions when a participants lies (functionalMRI, or

    fMRI).

    Older Brain Structures:

    o The Brainstem is the oldest part of the brain, beginning where

    the spinal cord swells and enters the skull. It is responsiblefor automatic survival functions.

    The Medulla [muh-DUL-uh] is the base of the brainstem

    that controls heartbeat and breathing.

    The Thalamus [THAL-uh-muss] is the brains sensory

    switchboard, located on top of the brainstem. It directs

    messages to the sensory areas in the cortex and

    transmits replies to the cerebellum and medulla.

    Reticular Formation is a nerve network in the brainstem

    that plays an important role in controlling arousal.

    o Cerebellum

    The little brain attached to the rear of the brainstem.

    It helps coordinate voluntary movements and balance.

    o The Limbic System:

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    The Limbic System is a doughnut-shaped system of

    neural structures at the border of the brainstem and

    cerebrum, associated with emotions such as fear,

    aggression and drives for food and sex. It includes the

    hippocampus, amygdala, and hypothalamus. The Amygdala [ah-MIG-dah-la] consists of two

    lima bean-sized neural clusters linked to the

    emotions of fear and anger.

    The Hypothalamus lies below (hypo) the

    thalamus. It directs several maintenance

    activities like eating, drinking, body temperature,

    and control of emotions. It helps govern the

    endocrine system via the pituitary gland.

    Reward Center:

    Rats cross an electrified grid for self-stimulation

    when electrodes are placed in the reward

    (hypothalamus) center (top picture). When the

    limbic system is manipulated, a rat will navigate

    fields or climb up a tree (bottom picture).

    The Cerebral Cortex:

    o A big part of the brain

    o The intricate fabric of interconnected neural cells that coversthe cerebral hemispheres. It is the bodys ultimate control

    and information processing center.

    o Structure of the Cortex:

    Each brain hemisphere is divided into four lobes that

    are separated by prominent fissures. These lobes are

    the frontal lobe (forehead), parietal lobe (top to rear

    head), occipital lobe (back head) and temporal lobe

    (side of head).

    o Functions of the cortex:

    The Motor Cortex is the area at the rear of the frontal

    lobes that control voluntary movements. The Sensory

    Cortex (parietal cortex) receives information from skin

    surface and sense organs.

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    Visual Function: A functional MRI scan shows the

    visual cortex is active as the subject looks at

    faces.

    Auditory Function: A functional MRI scans shows

    the auditory cortex is active in patients whohallucinate.

    Association Areas: More intelligent animals have

    increased uncommitted or association areas of

    the cortex.

    o Language:

    Aphasia is an impairment of language, usually caused

    by left hemisphere damage either to Brocas area

    (impaired speaking) or to Wernickes area (impaired

    understanding).

    o Specialization and Integration

    Brain activity when hearing, seeing, or speaking words

    o Why is it shaped the way that its shaped?

    To increase surface area in a way so that a baby can be

    born

    Our Divided Brain

    o The human brain is divided into two hemispheres.

    o The left hemisphere (at least in right-handed people) isprimarily responsible reading, writing, speaking,

    mathematics, and comprehension skills. It used to be termed

    the dominant brain.

    The Brains Plasticity

    o The brain is sculpted by our genes but also by our

    experiences.

    o Plasticity refers to the brains ability to modify itself after

    some types of injury or illness.

    o Young children who lose an entire hemisphere (left or right)

    may grow with near-normal cognitive abilities

    o But children who lose their frontal cortex (front of the brain)

    show major impairments in later life.

    Splitting the Brain:

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    o A procedure in which the two hemispheres of the brain are

    isolated by cutting the connecting fibers (mainly those of the

    corpus callosum) between them.

    o Split brain patients:

    With the corpus callosum severed, objects (apple)presented in the right visual field can be named.

    Objects (pencil) in the left visual field cannot.

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    29/09/2011 15:37:00