titres books biologie moléculaire

7/30/2019 titres books biologie molculaire

1/8

springer.com/librarybooks6 Springer News 12/2010Biomedicine

R. Aphasizhev, University o Caliornia, Irvine, CA,

USA (Ed.)

RNA and DNA EditingMethods and Protocols

Te recent expansion in diversity o RNA and

DNA editing types has stimulated the developmento many unique genetic, molecular, biochemical,

and computational approaches to biological

issues. In RNA and DNA Editing: Methods and

Protocols, leading experts in the eld introduce

methods developed over the last ew years to study

editing substrates, mechanisms o specicity, and

unctions o RNA and DNA editing enzymes and

complexes. Sections o the book are dedicated to

state-o-the art techniques which enable investiga-

tion o uracil insertion/deletion RNA editing in

mitochondrion o rypanosoma brucei, adenosine

to inosine RNA editing, cytidine to uracil RNA and

DNA editing, as well as tRNA editing and RNA

modications.

Features

7 Features cutting-edge methodologies ocused

on the study o this diverse eld o study

7 Includes unique genetic, molecular, biochem-

ical, and computational approaches 7 Contains

expert tips and implementation advice

From the contentsTree-Dimensional Reconstruction o rypano-

soma brucei Editosomes Using Single-Particle

Electron Microscopy.- iCODA: RNAi-Based

Inducible Knock-In System in rypanosoma

brucei.- Perturbing A-to-I RNA Editing Using

Genetics and Homologous Recombination.- Laser

Microdissection and Pressure Catapulting o SingleHuman Motor Neurons or RNA Editing Analysis.-

Biochemical Identication o A-to-I RNA Editing

sites by the Inosine Chemical Erasing (ICE)

Method.- Identiying mRNA Editing Deaminase

argets by RNA-Seq.- Mouse and Other Rodent

Models o C to U RNA Editing.- In vivo Analysis

o RNA Editing in Plastids.- Identiying Specic

rans-Factors o RNA Editing in Plant Mitochon-

dria by Multiplex Single Base Extension yping.

Fields of interestHuman Genetics; Enzymology

Target groups

Proessional/practitioner

A. Ayed, University o Toronto, ON, Canada; T. Hupp,

University o Edinburgh, Scotland, UK (Eds.)

p53

Tis volume, p53, was developed primarily as a

resource or access to key ideas in the eld that

have developed over the years including howtransgenics have been used to study p53, how

clinical genetics have identied and studied muta-

tions in p53 ound in human cancers, how p53

can be regulated by post-translational modica-

tion, and how key drug targets have been dened,

namely MDM2, which has provided undamental

approaches or dening how p53 can be acti-

vated with potential ly therapeutic eect. Te

key concepts in the chapters included provide a

perspective on key paradigms in the p53 eld.

Features

7 Discusses P53 Mutations in Human Cancers

7 Chapter on Regulation and Function o the

Original p53-Inducible p21 Gene 7 Presents keyideas in the eld

ContentsP53 Mutations in Human Cancers: Selection

versus Mutagenesis.- Lessons on p53 rom Mouse

Models.- P63, P73: Te Guardians Elder

Brothers.- Te Regulation o p53 Protein Function

by Phosphorylation.- Te p53-Mdm2 Loop: A

Critical Juncture o Stress Response.- Coopera-

tion between MDM2 and MDMX in the Regula-

tion o p53.- Regulation and Function o the

Original p53-Inducible p21 Gene.- p53 Localiza-

tion.- Modes o p53 Interactions with DNA in the

Chromatin Context.- p53s Dilemma in ranscrip-

tion: Analysis by Microarrays.- umor Viruses andp53.- p53 and Immunity.

Fields of interestCancer Research

Target groupsResearch

E. Ballestar, Bellvitge Biomedical Research Institute

(IDIBELL), Barcelona, Spain (Ed.)

Epigenetic Contributions inAutoimmune Disease

Tis volume ocuses on the relevance o epigenetic

mechanisms in autoimmune disease. It providesnew directions or uture research in autoimmune

disease.

Features7 Overview o some o the key concepts in

epigenetics, chromatin and the interaction with

transcription actors 7 Shows the specic inu-

ence o environmental actors to inuence or

trigger the autoimmune response 7 Discusses the

possibilities o using epigenetics-based therapies in

the context o autoimmune diseases 7 Presents

the application o novel methods to characterize

the epigenetic prole

ContentsAN INRODUCION O EPIGENEICS.-

CHROMAIN MECHANISMS REGULAING

GENE EXPRESSION IN HEALH AND

DISEASE.- EPIGENEIC CONROL OF

LYMPHOCYE DIFERENIAION.- EPIGEN-

EIC CONROL IN IMMUNE FUNCION.-

DNA MEHYLAION AND B-CELL AUOR

EACIVIY.- ENVIRONMENAL AGENS

AND AUOIMMUNE DISEASES.- EPIGEN-

EIC DYSREGULAION OF EPSEIN-BARR

VIRUS LAENCY AND DEVELOPMEN OF

AUOIMMUNE DISEASE.- DOES GENOMIC

IMPRINING PLAY A ROLE IN AUOIMMU-

NIY?.- A NEW EPIGENEIC CHALLENGE:

SYSEMIC LUPUS ERYHEMAOSUS.-EPIGENEIC DEREGULAION IN RHEUMA-

OID ARHRIIS.- PROSPECS FOR EPIGEN-

EIC COMPOUNDS IN HE REAMEN

OF AUOIMMUNE DISEASE.- PROFILING

EPIGENEIC ALERAIONS IN DISEASE.

Fields of interestBiomedicine general; Gene Function


Discount groupP

Due February 2011

2011. 250 p. 57 illus., 1 in color. (Methods in Molecular

Biology, Volume 718) Hardcover

7

$119.00ISBN 978-1-61779-017-1

Discount groupP

Due March 2011

2011. XVI, 200 p. 59 illus., 3 in color. (Molecular Biology

Intelligence Unit, Volume 1) Hardcover

7

$189.00ISBN 978-1-4419-8230-8

Discount groupP

Due January 2011

2011. XVI, 178 p. 22 illus. (Advances in Experimental

Medicine and Biology, Volume 711) Hardcover

7

$189.00ISBN 978-1-4419-8215-5
http://www.springer.com/978-1-61779-017-1http://www.springer.com/978-1-61779-017-1http://www.springer.com/978-1-4419-8230-8http://www.springer.com/978-1-4419-8230-8http://www.springer.com/978-1-4419-8215-5http://www.springer.com/978-1-4419-8215-5http://www.springer.com/978-1-4419-8215-5http://www.springer.com/978-1-4419-8230-8http://www.springer.com/978-1-61779-017-1


2/8


3/8


U. N. Das, UND Lie Science, Shaker Heights, OH, USA

Molecular Basis o Health andDisease

Te book describes how the balance between

pro- and anti-inammatory molecules is related

to health and disease. It is suggested that manydiseases are initiated and their progress is inu-

enced by inammatory molecules and a decrease

in the production and/or action o anti-inam-

matory molecules and this imbalance between

pro- and anti-inammatory molecules seems to

have been initiated in the perinatal period. Tis

implies that strategies to prevent and manage

various adult diseases should start in the perinatal

period. An alteration in the metaolism o essential

atty acids and their anti-inammatory molecules

such as lipoxins, resolvins, protecitns, maresins

and nitrolipids seems to play a major role in the

pathobiology o several adult diseases. Based on

these concepts, novel therapeutic approaches in

the management o insulin resistance, obesity,type 2 diabetes mellitus, metabolic syndrome,

cancer, lupus, rheumatoid arthritis and other auto-

immune diseases are presented.

Features

7 Perinatal origins o adult diseases 7 Adult

diseases as low-grade systemic inammatory

conditions 7 Inammation as the basis o

obesity, insulin resistance, metabolic syndrome

and cancerImbalance in the pro- and anti-inam-

matory molecules as the basis o adult diseases

7 Altered metabolism o essential atty acids and

eicosanoids in the pathobiology o adult diseases

Fields of interestBiomedicine general; Human Physiology;

Molecular Medicine

Target groupsProessional/practitioner

T. L. DeWeese, M. Laiho, Johns Hopkins University,

Baltimore, MD, USA (Eds.)

Molecular Determinants oRadiation Response

Molecular Determinants o Radiation Response

includes chapters by expert authors who detailthe present understanding o key DNA damage

response pathways and proteins. Te chapters

include comprehensive discussions on where and

how specic alterations in unction o these path-

ways and proteins result in substantive modica-

tions o cellular response to DNA injury. Given the

importance o therapies that induce DNA injury

in the management o human disease, this book

is timely and relevant or basic and translational

researchers, as well as clinicians alike.

Features

7 Includes chapters by expert authors who detail

the present understanding o key DNA damage

response pathways and proteins 7 Presentscomprehensive discussions on where and how

specic alterations in unction o these pathways

and proteins result in substantive modications o

cellular response to DNA injury 7 A timely and

relevant text or basic and translational researchers

From the contentsMolecular Basis o the DNA Damage Responses.-

AM signaling and DNA Damage.- H2AX in

DNA Damage Response.- Dynamic Imaging o

DNA Damage Foci.- DNA Damage Signaling

Downstream o AM.- Checkpoint Control

and Radiation.- Chromatin Responses to DNA

Damage.-DNA Damage Response and Senes-

cence.- C. elegans and DNA Damage.- Modulationo Radiation Responses Opportunities or Tera-

peutic Exploitation.- Te Stem Cell and Radia-

tion.- Role o the Cell Membrane in Signaling

Radiation Injury.- Hypoxia and Modulation o

Cellular Radiation Response.- Role o PARP and

PARP Inhibition in Cellular Response to Radia-

tion.- Anti-angiogenic Terapies and Radiation

Responses.- Gene Terapy and Radiation.- Radia-

tion-mediated Molecular argeting.

Fields of interestCancer Research; Pharmacology/oxicology

Target groups

Research

A. El-Baz, Bioengineering Department, University

o Louisville, KY, USA; R. Acharya U, Department

o Computer and Electrical Engineering, Ngee Ann

Polytechnic, Singapore; M. Mirmehdi, Department o

Computer Science, University o Bristol, England;

J. Suri, Biomedical Technologies Inc., Denver, CO, &

Af- Idaho State University, Idaho, ID, USA (Eds.)

Multi ModalityState-o-the-Art MedicalImage Segmentation andRegistration MethodologiesVolume 1

With the advances in image guided surgery or

cancer treatment, the role o image segmenta-

tion and registration has become very critical.

Te central engine o any image guided surgery

product is its ability to quantiy the organ or

segment the organ whether it is a magnetic reso-

nance imaging (MRI) and computed tomography

(C), X-ray, PE, SPEC, Ultrasound, and Molec-ular imaging modality. Sophisticated segmentation

algorithms can help the physicians delineate better

the anatomical structures present in the input

images, enhance the accuracy o medical diagnosis

and acilitate the best treatment planning system

designs. Te ocus o this book in towards the state

o the art techniques in the area o image segmen-

tation and registration.

Features7 3D Deormable models or medical imaging

segmentation 7 Covers skin, lung, brain and

retinal cancers Ultrasound and MRI image

registration 7 Advanced techniques in brain

segmentation and registration

Fields of interestBiomedicine general; Biomedical Engineering;

Image Processing and Computer Vision

Target groupsProessional/practitionerDiscount group

P

Due March 2011

2011. XX, 1460 p. Hardcover

7

approx. $239.00ISBN 978-94-007-0494-7

Discount groupP

Due March 2011

2011. Approx. 350 p. 34 illus., 25 in color. (Current Cancer

Research) Hardcover

7

approx. $159.00ISBN 978-1-4419-8043-4

Discount groupP

Due February 2011

2011. 650 p. 250 illus., 125 in color. Hardcover

7

approx. $239.00ISBN 978-1-4419-8194-3


4/8

springer.com/librarybooks 9Springer News 12/2010 Biomedicine

A. El-Baz, Bioengineering Department, University

o Louisville, USA; R. Acharya U, Department o

Computer and Electrical Engineering, Ngee Ann

Polytechnic, Singapore; A. Laine, Department o

Biomedical Engineering, Columbia University, USA;

J. Suri, Biomedical Technologies Inc., Denver, CO, &

Af.- Idaho State University, Idaho, ID, USA (Eds.)

Multi ModalityState-o-the-Art MedicalImage Segmentation andRegistration MethodologiesVolume II

With the advances in image guided surgery or

cancer treatment, the role o image segmenta-

tion and registration has become very critical.

Te central engine o any image guided surgery

product is its ability to quantiy the organ or

segment the organ whether it is a magnetic reso-

nance imaging (MRI) and computed tomography

(C), X-ray, PE, SPEC, Ultrasound, and Molec-ular imaging modality. Sophisticated segmentation

algorithms can help the physicians delineate better

the anatomical structures present in the input

images, enhance the accuracy o medical diagnosis

and acilitate the best treatment planning system

designs. Te ocus o this book in towards the state

o the art techniques in the area o image segmen-

tation and registration.

Features7 Combining Registration and Segmentation

echniques 7 Segmentation Application to Pros-

thesis Design and Brain 7 Role o Segmentation

in Autistic and Normal Brains 7 Ocular Termo

graphic Sequence Analysis 7 3D UltrasoundImage Segmentation

Fields of interestBiomedicine general; Imaging / Radiology; Image

Processing and Computer Vision


Z. Kahn, T. Tot, Uppsala University, Sweden (Eds.)

Breast Cancer, aHeterogeneous Disease EntityThe Very Early Stages

Te volume raises attention to the need o a

completely new approach to breast cancer basedon the knowledge collected on early breast cancer

in the past two decades. Te chapters are contrib-

uted by experts o all the elds participating in

the clinical research and care o breast cancer. Te

practical importance o such a book is underlined

by the increasing number o breast cancer cases,

and also the increasing proportion o early stage-

cases. Te ultimate goal o the book is to point to

the heterogeneous nature o the disease which is

more striking and has more importance in care at

the very early stages than at the more advanced

stages. Te book recommends the utilization o

all the inormation provided by multimodality

imaging and special pathological methods, a new

classication system and therapeutic guidelinessince early breast cancers should not be treated

based on experience obtained with palpable

tumors. No similar book has been yet released to

the market.

Features7 Proposes a new approach (paradigm shif)

Multidisciplinary basis 7 Healthcare importance

and practicability 7 Similar book is absent on the

market 7 Relatively wide readership

Fields of interestCancer Research; Human Physiology; Pharma-

cology/oxicology


R. P. Rij, University Nijmegen, The Netherlands (Ed.)

Antiviral RNAiConcepts, Methods, and Applications

Viruses and RNAi share an intricate relationship

at many levels. RNAi is an important antiviral

deense mechanism in plants and invertebrates,microRNAs o viral or cellular origin aect

many aspects o virus biology, and replication

o many, i not all, mammalian viruses can be

suppressed by RNAi. Antiviral RNAi: Concepts,

Methods, and Applications provides a collection

o protocols or the analysis o viral small RNAs

and natural antiviral RNAi responses as well as or

the development and optimization o RNAi-based

antiviral drugs. As RNAi is a central regulatory

mechanism in the cell, the methods in this volume

can also be applied out o the context o a virus

inection.

Features

7 Includes cutting-edge methods and proto-cols 7 Provides step-by-step detail essential or

reproducible results 7 Contains key notes and

implementation advice rom the experts

From the contentsDeense and counter-deense in the RNAi-based

antiviral immune system in insects.- RNAi and

cellular miRNAs in inections by mammalian

viruses .- Viral miRNAs.- Progress in RNAi-based

antiviral therapeutics.- Chemical modication

o small interering RNA.- Viral small RNA

cloning and sequencing.- Visitor, an inormatic

pipeline or analysis o viral siRNA sequencing

datasets.- Computational prediction o viral

miRNAs.- Detection o Viral microRNAs byNorthern Blot Analysis.- Detection o viral

microRNA with S1 Nuclease Protection assay.-

Characterization o RISC associated adenoviral

small RNAs.- Identication o Viral Suppressors

o RNAi by a Reporter Assay in Drosophila S2

Cell Culture.- Dicer assay in Drosophila S2 cell

extract.- Slicer activity in Drosophila melanogaster

S2 extract.- Gel Mobility Shif Assays or RNA-

binding viral RNAi suppressors.

Fields of interestHuman Genetics; Virology

Target groups

Proessional/practitioner

Discount groupP

Due February 2011

2011. 650 p. 250 illus., 125 in color. Hardcover

7

approx. $239.00ISBN 978-1-4419-8203-2

Discount groupP

Due March 2011

2011. X, 490 p. Hardcover

7

$209.00ISBN 978-94-007-0488-6

Discount groupP

Due April 2011



7

approx. $139.00ISBN 978-1-61779-036-2


5/8


S. D. Satyanarayanajois, University o Louisiana,

Monroe, LA, USA (Ed.)

Drug Design and DiscoveryMethods and Protocols

Research in the pharmaceutical sciences and

medicinal chemistry has taken an important newdirection in the past two decades with a ocus on

large molecules, especially peptides and proteins,

as well as DNA therapeutics. In Drug Design and

Discovery: Methods and Protocols, leading experts

provide an in-depth view o key protocols that are

commonly used in drug discovery laboratories.

Covering both classic and cutting-edge techniques,

this volume explores computational docking,

quantitative structure-activity relationship

(QSAR), peptide synthesis, labeling o peptides and

proteins with uorescent labels, DNA-microarray,

zebrash model or drug screening, and other

analytical screening and biological assays that are

routinely used during the drug discovery process.

Features

7 Explores computational, spectroscopic, analyt-

ical, purication, and molecular biology methods,

as well as cellular assays 7 Provides an in-depth

view o protocols used most commonly in drug

discovery laboratories 7 Features expert tips and

vital implementation advice

From the contentsVirtual Screening or Lead Discovery.- Computer-

Aided Drug Discovery and Development.- Using

Active Site Mapping and Receptor-Based Pharma-

cophore ools: Prelude to Docking and De Novo/

Fragment-Based Ligand Design.- Methods or

Evaluation o Structural and Biological Propertieso Anti-Invasive Natural Products.- Solid-Phase

Peptide Synthesis Using Microwave Irradia-

tion.- Fluorescent and Lanthanide Labeling or

Ligand Screens, Assays, and Imaging.- DNA-

Directed Assembly Microarray or Protein and

Small Molecule Inhibitor Screening.- Selection o

Peptide Ligands or Human Placental ranscytosis

Systems Using In vitro Phage Display.

Fields of interestPharmacology/oxicology; Laboratory Medicine


M. Schwanstecher, TU Braunschweig, Germany (Ed.)

Diabetes Perspectives inDrug Therapy

Te chapters o this book report cutting-edge

research on molecular events in adiposity and type

2 diabetes, thus opening the way or innovativedrug-based therapeutic strategies. It addresses

all those who wish to keep in touch with recent

developments in the eld.

Features7 Features excellent reviews o international

experts on cutting edge diabetes research

7 Provides a detailed up to date overview o

cellular and molecular mechanisms involved in

obesity driven development o type 2 diabetes

7 Focuses on potential novel drug targets, thus

opening the way or innovative strategies in

diabetes and obesity therapy

ContentsPreace. argeting type 2 diabetes. Dual acting

and pan-PPAR activators as potential anti-diabetic

therapies. GLP-agonists and Dipeptidyl-Peptidase

IV Inhibitors. Cannabinoids and endocan-

nabinoids in metabolic disorders with ocus on

diabetes. SGL Inhibitors as New Terapeutic

ools in the reatment o Diabetes. Inhibitors

o 11b-hydroxysteroid dehydrogenase type 1 in

antidiabetic therapy. Nampt and its potential role

in inammation and type 2 diabetes. Inhibition

o ganglioside biosynthesis as a novel therapeutic

approach in insulin resistance. Overcoming Insulin

Resistance with Ciliary Neurotrophic Factor. Ter-

mogenesis and related metabolic targets in

anti-diabetic therapy. Interleukin targeted therapyor metabolic syndrome and type 2 diabetes. Fruc-

tose-1, 6-Bisphosphatase Inhibitors or Reducing

Excessive Endogenous Glucose Production in ype

2 Diabetes.

Fields of interestPharmacology/oxicology; Human Physiology;

Cell Biology


K. Sderhll, Uppsala University, Sweden (Ed.)

Invertebrate Immunity

It can be seen that the insects are the still attracting

most research and researchers. However, an

increasing interest is emerging to study new inver-

tebrate groups, especially those where the genome

is known. Even though Drosophila has been andstill is an excellent model or immune studies, it is

now clear that there are great dierences between

immune responses in Drosophila and that o

several other invertebrates, which indeed calls or

more research on other invertebrates

Features

7 Describes diversity between dierent inverte-

brate animal groups 7 Shows that the prophe-

noloxidase activating system and the induction

o the oll pathway in an insect share the same

proteolytic cascade 7 Displays a growing interest

in invertebrate immunity, which is the study o the

link between physiology and immunity

ContentsCnidarian immunity: a tale o two barriers.-

gastropod immunobiology.- bivalve immunity.-

earthworm immunity.- lech immunity: rom brain

to peripheral - responses.- innate immunity in

c. elegans.- immunocompetent molecules and

their response network in horseshoe crabs.- tick

innate immunity.- beetle immunity.- immunity in

lepidopteran insects.- y immunity: recognition o

pathogens and induction o immune responses.-

mosquito immunity.- crustacean immunity.-

echinoderm immunity.- urochordate immunity.

Fields of interest

Biomedicine general; Immunology


Discount groupP

Due February 2011



7

$119.00ISBN 978-1-61779-011-9

Discount groupP

Due April 2011

2011. Approx. 400 p. (Handbook o Experimental

Pharmacology, Volume 203) Hardcover

7

approx. $469.00ISBN 978-3-642-17213-7

Discount groupP

Due January 2011

2011. XXIV, 314 p. 63 illus., 13 in color. (Advances in

Experimental Medicine and Biology, Volume 708)

Hardcover

7

$209.00ISBN 978-1-4419-8058-8


6/8


R. L. Thurmond, Johnson & Johnson Pharmaceutical

Research & Development, LLC, San Diego, CA, USA

(Ed.)

Histamine in Inammation

Te year 2010 marks the centennial or the iden-

tication o histamine and the rst glimpse o its

many physiological unctions. From these initialndings a rich tapestry o research has uncovered

roles or histamine in almost every physiological

process with new ndings emerging every year.

Tese diverse roles o histamine have made or

ertile ground or the discovery o novel therapeu-

tics, and these drugs have been so successul that

the term antihistamine has entered the common

lexicon. Tis book is an attempt to give a snapshot

in time as to the current understanding o the role

o histamine in just one important therapeutic

areainammation.

Features7 Provides an overview o the pharmacology o

the our histamine receptors and describes howhistamine is synthesized and the insights derived

rom mice where this synthesis is disrupted

7 Discusses the important role o histamine

in neurotransmission and or the treatment o

various neurological disorders 7 Explains the

uture o antihistamine research and the poten-

tial or novel antihistamines targeting the newest

members o the histamine receptor amilythe H3

and H4 receptors

ContentsOne Hundred Years o Histamine Research.-

Molecular Pharmacology o the Four Histamine

Receptors.- Histamine Synthesis and Lessons

Learned rom Histidine Decarboxylase DecientMice.- Histamine in Allergic Rhinitis.- Te Role

o Histamine in Ocular Allergy.- Te Role o Hista-

mine in Asthma.- Antihistamines in the reatment

o Urticaria.- Histamine and Antihistamines in

Atopic Dermatitis.- Histamine, Immune Cells and

Autoimunity.- Histamine in Neurotransmisi on

and Brain Diseases.- Histamine in Normal and

Malignant Cell Prolieration.- Te Future Antihis-

tamines: Histamine H3 and H4 Receptor Ligands.

Fields of interestBiomedicine general; Human Physiology

Target groups

Research

J. Vrkonyi, Semmelwies University, Budapest,

Hungary (Ed.)

The MyelodysplasticSyndromes

Features

7 Updated patient stratication or the dierenttherapeutical modalities 7 Updated disease clas-

sication 7 Update o the available therapies

Contents1. PREFACE.- 2. Te history o the Myelodys-

plastic Syndromes.- 3. Susceptibility to MDS: DNA

repair and detoxication genes.- 4. Myelodys-

plastic syndromes/neoplasms: Morphological

and Immunohistochemical eatures and standard

evaluation.- 5. Diagnostic Criteria and Clas-

sication o Myelodysplastic Syndromes.- 6.

Cytogenetics o MDS.- 7. Molecular changes in

myelodysplastic syndrome.- 8. Prognostic Scoring

in MDS.- 9. Flow Cytometry in Myelodysplastic

Syndromes.- 10. MDS as an Autoimmune Process.-11. Te Myelodysplastic Overlap Syndromes.- 12.

Iron and copper Metabolismin the Myelodysplastic

Syndromes.- 13. Pathogenesis and Management

o Iron Overload in MDS.- 14. Cytokines in MDS.

Abnormalities and treatment.- 15. Terapeutic

Modalities and new molecular targets in MDS.-

16. Haematopoietic Stem Cell ransplantation in

MDS or Adults.- 17. JMML and Myelodysplastic

Syndrome in children.

Fields of interestBiomedicine general; Hematology; Medicine/

Public Health, general


J. Zhou, G. Xie, Chinese Academy o Sciences,

Beijing, China; X. Yan, National Institute o Standards

and Technology (NIST), Rockville, MD, USA

Encyclopedia o TraditionalChinese Medicines MolecularStructures, Pharmacological

Activities, Natural Sources andApplicationsVol. 1: Isolated Compounds A-C

Tis set o six volumes provides a systematic

and standardized description o 23,033 chemical

components isolated rom 6,926 medicinal plants,

collected rom 5,535 books/articles published in

Chinese and international journals. A chemical

structure with stereo-chemistry bonds is provided

or each chemical component, in addition to

conventional inormation, such as Chinese and

English names, physical and chemical proper-

ties. It includes a name list o medicinal plants

rom which the chemical component was isolated.Furthermore, abundant pharmacological data or

nearly 8,000 chemical components are presented,

including experimental method, experimental

animal, cell type, quantitative data, as well as

control compound data. Te seven indexes allow

or complete cross-indexing.

Features7 For the rst time, a collection o more than

20,000 chemical components o medicinal plants

or studying CM is provided 7 Has a systematic

and integrated approach 7 With seven indexes

the inormation in the book can be retrieved in

multiple ways

ContentsIntroduction.- How to Use Tis Book.- Abbrevia-

tions and Symbols.- Cancer Cell Codes in Phar-

macological Models.-Isolated Compounds AC

(Entries 1-4594).

Fields of interestPharmaceutical Sciences/echnology; Pharma-

cology/oxicology; Biochemistry, general


Discount groupP

Due March 2011

2011. XVIII, 144 p. 24 illus. (Advances in Experimental

Medicine and Biology, Volume 709) Hardcover

7

$189.00ISBN 978-1-4419-8055-7

Discount groupP

Due March 2011

2011. X, 490 p. Hardcover

7

$209.00ISBN 978-94-007-0439-8

Discount group

P

Due February 2011

2011. 594 p. Hardcover

7 $349.00

ISBN 978-3-642-16734-8

Also available as a setISBN 978-3-642-17733-0
http://www.springer.com/978-1-4419-8055-7http://www.springer.com/978-1-4419-8055-7http://www.springer.com/978-94-007-0439-8http://www.springer.com/978-94-007-0439-8http://www.springer.com/978-3-642-16734-8http://www.springer.com/978-3-642-16734-8http://www.springer.com/978-3-642-17733-0http://www.springer.com/978-3-642-17733-0http://www.springer.com/978-3-642-16734-8http://www.springer.com/978-94-007-0439-8http://www.springer.com/978-1-4419-8055-7


7/8




an Technology (NIST), Rockville, MD, USA


Activities, Natural Sources andApplicationsVol. 2: Isolated Compounds D-G






















multiple ways

ContentsIsolated Compounds DG (Entries 4595-9185).




J. Zhou, Chinese Academy o Sciences, Beijing, China;

G. Xie, Beijing, China; X. Yan, National Institute o

Standards an Technology (NIST), Rockville, MD, USA


Activities, Natural Sources andApplicationsVol. 3: Isolated Compounds H-M






















multiple ways

ContentsIsolated Compounds HM (Entries 9186-15227).








Activities, Natural Sources andApplicationsVol. 4: Isolated Compounds N-S






















multiple ways

ContentsIsolated Compounds NS (Entries 15228-20574).




Discount groupP

Due February 2011

2011. XVI, 574 p. Hardcover

7 $349.00

ISBN 978-3-642-16737-9


Discount groupP

Due February 2011


7 $349.00

ISBN 978-3-642-16746-1


Discount groupP

Due February 2011


7 $349.00

ISBN 978-3-642-16778-2

http://www.springer.com/978-3-642-16737-9http://www.springer.com/978-3-642-16737-9http://www.springer.com/978-3-642-17733-0http://www.springer.com/978-3-642-16746-1http://www.springer.com/978-3-642-16746-1http://www.springer.com/978-3-642-17733-0http://www.springer.com/978-3-642-16778-2http://www.springer.com/978-3-642-16778-2http://www.springer.com/978-3-642-17733-0http://www.springer.com/978-3-642-17733-0http://www.springer.com/978-3-642-16778-2http://www.springer.com/978-3-642-17733-0http://www.springer.com/978-3-642-16746-1http://www.springer.com/978-3-642-17733-0http://www.springer.com/978-3-642-16737-9


8/8






Activities, Natural Sources andApplicationsVol. 5: Isolated Compounds T-Z, References,

TCM Plants and Congeners










ties. It includes a name list o medicinal plantsrom which the chemical component was isolated.

Furthermore, abundant pharmacological data or






Features

7 For the rst time, a collection o more than





multiple ways

ContentsIsolated Compounds Z (Entries 20575-23033).-

Reerences or Isolated Compounds.- CM

Original Plants and Congeners (Entries 0001-

6926).- Key Reerences.








Activities, Natural Sources andApplicationsVol. 6: Indexes






















multiple ways

ContentsIndexes.- Compound Pharmacological Activity

Index.- Compound Molecular Formula Index.-

Compound Side Name Index.- CM Plant English

Name Index.- CM Plant PINYIN and Chinese

Name Index.- CM Plant Eects Index.- CM

Plant Indications Index.




Discount groupP

Due February 2011


7 $349.00

ISBN 978-3-642-16740-9


Discount groupP

Due February 2011


7 $349.00

ISBN 978-3-642-16743-0

http://www.springer.com/978-3-642-16740-9http://www.springer.com/978-3-642-16740-9http://www.springer.com/978-3-642-17733-0http://www.springer.com/978-3-642-16743-0http://www.springer.com/978-3-642-16743-0http://www.springer.com/978-3-642-17733-0http://www.springer.com/978-3-642-17733-0http://www.springer.com/978-3-642-16743-0http://www.springer.com/978-3-642-17733-0http://www.springer.com/978-3-642-16740-9

Documents

titres books biologie moléculaire