Les institutions de recherche et de financement

EUROPE

Guillaume FUSAI, représentant aux comités de programme Horizon 2020, Ministère de lʼEnseignement supérieur, de la Recherche et de lʼInnovation

22 mai 2018 – Dynamiser la recherche

2

Biologie - santéau sein de Horizon 2020

3

Horizon 2020 - Challenges

The Framework programme for research and Innovation 2014-2020

ü Reinforce UE position in the world in research, innovation and technologies ;ü Develop UE competitivness through investment in technologies and new creative jobs for a « smart, sustainable, inclusive » growth;ü Reinforce Europe research attractivness;ü Taking into account European citizen concerns (health, environment, new energy...) and bring solutions and answers to societal challenges.

4

EXCELLENCESCIENTIFIQUE

PRIMAUTÉINDUSTRIELLE

DÉFISSOCIÉTAUX

3 PRIORITÉS

PILIER 1 PILIER 2 PILIER 3

Diffusion de l’excellence et élargissement de la participation

Science pour et avec la sociétéInstitut Européen d’Innovation et de Technologie

(EIT) Euratom

Programmes Transversaux

Structure du programme Horizon 2020

24,4 Md€ 17,0 Md€ 29,7 Md€

5

Health, demographicchange and well-being

Food security and bioeconomy

Secure, clean and efficient Energy

Smart, green and integrated transport

Climate action

Inclusive, innovativeand reflective societies

Secure societies

EXCELLENTSCIENCE

INDUSTRIALLEADERSHIP

SOCIETALCHALLENGES

Marie Sklodowska Curie Actions

ERC European Research Council

FETFuture Emerging Technologies

Research Infrastructures

Key Enabling Technologies• TIC• NMBPNanotechnologies, Advanced materials, Biotechnology, Advance manufacturing and processing, Photonics, Microelectronics• Espace

Access to risk finance

Innovation in SMEs

La santé dans Horizon 2020

6

Health, demographicchange and well-being

Food security and bioeconomy

Secure, clean and efficient Energy

Smart, green and integrated transport

Climate action

Inclusive, innovativeand reflective societies

Secure societies

EXCELLENTSCIENCE

INDUSTRIALLEADERSHIP

SOCIETALCHALLENGES

Marie Sklodowska Curie Actions

ERC European Research Council

FETFuture Emerging Technologies

Research Infrastructures

Key Enabling Technologies• TIC• NMBPNanotechnologies, Advanced materials, Biotechnology, Advance manufacturing and processing, Photonics, Microelectronics• Espace

Access to risk finance

Innovation in SMEs

La santé dans Horizon 2020

707/06/2018

1 2 3 4 5 6 7 8 9

Basic Research

Researchideas and protocols

Initial proof ofconcept (in

vitro & in vivo models)

PoC and safety

Preclinicalstudies (GLP)

+ toxicity

Clinical Phase1

Clinical Phase2

Clinical Phase3

Post MarketStudies and surveillance

1 2 3 4 5 6 7 8 9

Basic PrinciplesObserved

TechnologyConcept

Formulated

ExperimentalProof of Concept

Technologyvalidation in

lab

Technologyvalidation in

relevant environment

Demonstrationin relevant

environment

Demonstrationin operationalenvironment

System complete and

qualified

Successfulmission

operations

TRL = Technology Readiness Level – TRL appliquées au domaine pharmaceutique

ERC

FET

Projets collaboratifs: Défi Santé + SC2, SC5, SC6, ICT, NMBP

Actions Marie-Curie

SME Instrument

Fast Track to Innovation

Infrastructures de Recherche

Projets collaboratifs: ERA-Net, Programmation conjointe (JPI & EJP)

IMI

EDCTP

PRIMA

EIT Health

Programmes subventionnés et Positionnement TRL

807/06/2018

Budget du Défi Santé SC1 dans H2020

9

SC1 AdvisoryGroup (AG)

Consultation

Member States via PC Member

Input

Jan. – Jun. 2016

French National Strategy

Commission

WP 2018-2020October 2017

Stakeholders

July 2016

STRATEGY

IMPLEMENTATION

French Scientific community via GTN

Discussion

Elaboration du Work Programme 2018-2020

DraftJan. – Sept. 2017

Jan. – Sept. 2017

10

Un resultat final

1107/06/2018

Contexte politique du défi Santé 2018-2020

Focus Area transverses à tous les derniers appels H2020• Objectifs de développement durable et l‘Accord de Paris sur le climat

(COP21) : Ø Appels Low Carbon, climate resilient future (LC)Ø Appels Connecting economic and environmental gains – the

Circular Economy (CE)• Digital Single Market Strategy: Accélérer la digitalisation de l’EuropeØAppels Digitising and transforming European industry and services

(DT)ØEuropean Open Science Cloud

• Renforcer la Sécurité de l’Union européenne:Ø Appels Boosting the effectiveness of the Security Union (SU)

La Stratégie 3 « Os » : Open Innovation, Open Science, Open to the World

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Better health and care, economic growth and sustainable health systems- Personalised medicine - Innovative health & care industry- Global health- Sustainable and evidence based health and care systems

Decoding the role of the overall environment for health and well-

being

Human exposome – global changes and health

Digital transformation in Health and Caree-Health and m-HealthICT for Active and Healthy Ageing

Trusted Big Data solutions and Cybersecurity for Health and Care

Priorités pour 2018 - 2020

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Call 1. Better Health and care, economic growth and sustainable health systems, (21 calls, 11 CSA)

Call 2. – Digital transformation in Health and Care (8 calls, 5 CSA)

Call 3. – Trusted digital solutions and Cybersecurity in Health and Care (2 calls, 1 CSA)

Budget 2018-2019923 M€

Budget 2018-2019 186,6 M€ Budget 2018-2019

71M€

1.1 Personalised medicine1.2 Innovative health and care industry1.3 Infectious diseases and improving global health1.4. Innovative health and care systems -Integration of care1.5 Decoding the role of the environment for health and well-being

Structure du programme de travail 2018 - 2020

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Des critères d’évaluation simples et uniformesCritères d’évaluation

Impact• Réaliser les impacts listés dans le programme de travail correspondant au topic ;

• Renforcer la compétitivité et la croissance des entreprises en développant des innovations répondant aux besoins des marchés européens et globaux ;

• capacité d’innovation et d’intégration de nouvelles connaissances ;

• Prendre en compte les autres impacts environnementaux et sociétaux importants ;

• Mesure de disséminationconvaincantes, incluant la gestion des droits de propriétés intellectuelles et l’exploitation des résultats

Excellence• Clarté et pertinence des objectifs ;

• crédibilité de l’approche proposée ;

• bien-fondé du concept, incluant la multidisciplinarité, si c’est pertinent ;

• degré d’ambition du projet, potentiel d’innovation, et jusqu’à quel point le projet va au delà de l’état de l’art

Qualité et efficacité de la mise en œuvre

• cohérence et efficacité du plan de travail ("workplan"), incluant l’adéquation de la répartition des tâches et des ressources ;

• compétences et expériences des participants, complémentarité des participants individuellement, ainsi que du consortium dans son ensemble ;

• Adéquation des structuresde management et des procédures, incluant la gestion des risques

http://ec.europa.eu/research/participants/data/ref/h2020/wp/2014_2015/annexes/h2020-wp1415-annex-h-esacrit_en.pdf

- Appels en 1 étape Seuils : Excellence (4/5) , Impact (4/5), Implementation (3 /5) Total: 12/15

- Appels en 2 étapes Seuil flottant en 1ère étape (passage du nombre de projets dont la somme des budgets demandés correspond à 3 fois le budget disponible )

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1.1 Personalised Medecine Budg.Projet

BudgetTotal Type

BHC-03 2018 Exploiting research outcomes and application potential of the human microbiome for personalised prediction and prevention and treatment of disease 13-14 50 RIA

Develop personalised approaches and clinical tools to predict and prevent diseases byintegration of high quality microbiome and other -omics data produced by large scaleinitiatives- Production of new data to deliver more valuable tools- Related topics in SC2 and IMI

BHC-05 2018 International flagship collaboration with Canada for human data storage, integration and sharing for developing personalised medicine approaches 6 40 RIA

Improving international collaboration in data repositories, developing modelsand methods for data deposition, curation and exchange procedures(interoperability).- Multidisciplinary approach is key aspect- Several independent projects funded but “could” be coordinated by an existingconsortium

BHC-01 2019 Understanding causative mechanisms in co- and multimorbities 4-6 70 RIAIdentify causative mechanisms combining mental and physical disorders via theintegration of Basic, pre-clinical and/or clinical research (clinical trials excluded)- Biomarkers development for diagnostic and monitoring- Continuation of PHC-3 (WP 2014-2015)

BHC-02 2019 Systems approaches for the discovery of combinatorial therapies for complex disorders 4-6 50 RIABuild more sophisticated computational framework to predict patient responsesto combinatorial therapies : pre-clinical and clinical validation- Project focus on marketed therapeutic intervention and/or products in finalstage of development (phase 1 and 2 excluded)-Drug repurposing is included in the scope

Call 1. Better Health and care, economic growth and sustainable health systems

18 avril 18

18 avril 18

02 Oct. 18 - 16 Apr. 19

02 Oct. 18 - 16 Apr. 19

1607/06/2018

1.2 Innovative Health care industry Budg.Projet

BudgetTotal Type

BHC-09 2018 Innovation platforms for advanced therapies of the future 12-15 50 RIA

Creation of knowledge and exploitation platforms around innovative concepts for

advanced therapies- To build possible new therapeutic approaches

- Component : Basic biology and its mode of action, proof-of-concept, safety, efficacy

etc …

- Business model to exploit results, outreach and public information activities

- Advanced therapies definition : EC Regulation 1394/2007

BHC-07 2019 Regenerative medicine : from new insights to new applications 6-8 50 RIA

Develop regenerative processes to address unmet clinical needs of large patient group

-Explain how the approach is regenerative

-Any step of the innovation chain

-Conventional method or device alone are excluded

- Show how it will be delivered to patient, potential exploitation and regulatory aspects

BHC-10 2019 Innovation Procurement : Next generation sequencing (NGS) for routine diagnosis 9-11 40 PCP

18 avril 18

16 avril 19

Call 1. Better Health and care, economic growth and sustainable health systems (suite)

02 Oct. 18 - 16 Apr. 19

17

07/06/2018

1.3 Infectious diseases and improving global health Budg.Projet

BudgetTotal Type

BHC-15 2018 New anti-infective agents for prevention and/or treatment of neglected infectious diseases (NID) 5-10 52 RIAThe call targets the Neglected infectious diseasesFurther development of vaccines and/or drugs candidates- bridge the gap between preclinical and clinical development - help advance already existing candidates along the development pipeline- Neglected viral disease excluded- Participation of disease endemic countries

BHC-16 2018Global Alliance for Chronic Disease (GACD) – Scaling-up of evidence-based health interventions at population level for the prevention, detection, and management of hypertension and/or diabetes

2-4 20 RIA

Scale-up interventions at population level for hypertension and/or diabetes prevention, detection, and management/Focus on Low and Medium Income Countries (LMIC) or vulnerable population in High Income Countries (HIC)- Proposal addressing the comorbidities of hypertension and diabetes are encouraged

BHC-21 2018Research on HIV and/or tuberculosis and/or hepatitis C in patients with mono-, co-infections or comorbidities in the contest of the collaboration between the European Union and the Russian Federation

2-3 10 RIA

TB: To investigate biomarkers or new diagnostic tests for early screening of TB risk groups for TBinfection and identification of antimicrobial drug resistance.HIV: To investigate the susceptibility to HIV and/or disease progression rate after infection, including various HIV serotypes, development of genetically-defined adverse effects (AE) during antiretroviral therapy (ART) and concomitant diseases (comorbidities and co-infections, including with tuberculosis).HCV: To evaluate the genetic determinants of the virus and the host, comorbid conditions that can beinvolved in disease progression and HCV treatment strategies.- Address one or more subtopics/Use of already established European cohort networks

06 Fev. 18 - 04 sep 18

18 avril 18

18 avril 18

Call 1. Better Health and care, economic growth and sustainable health systems (suite)

BHC-18 2018 Translational collaborative cancer research between Europe and the Community of Latin America and Caribbean States (CELAC) 1-3 25 RIA

Identify specific patient groups in view of improving one or more of the following aspect : screening,early detection, diagnosis, and/or prognosisBuild on diverse genetic backgrounds, risk factors, cancer incidence […] in European and CELACcountry. Integrate molecular, behavioural, nutritional, clinical, social and environmentalepidemiology data from cohorts; registries, biobank …

18 avril 18

18

BHC-13 2019Mining big data for early detection in infectious disease threats driven by climate change and other factors 12-15 30 RIA

Development of technology which allows the pooling, access analysis and sharing of relevant dataInnovative bioinformatics and modelling methodologies (risk modelling and mapping)Ready to use Analytical tools for early warning, risk assessment and monitoring of (re)emerginginfectious diseases threats- Data from a wide range of relevant sources (NGS, surveillance data, societal data)- Data privacy and Data security must be taken into account

BHC-14 2019Stratified host-directed approaches to improve prevention and/or treatment of infectious disease 6-10 95 RIA

Develop novel therapeutic or preventive approaches on the basis of specific factors identified in thehost or the host-pathogen interaction - Stratification of individuals based on theses characteristicsand tailor the treatment or the preventive measure accordinglyTest emerging concepts in drug and/or vaccine development in order to address the problem ofantimicrobial drug resistance and to optimize therapeutic, curative or preventive measures againstinfectious diseases of major concern for Europe- Differences in factors such as age, gender and genetic variation among the human populationshould be taken into consideration- The proposals should focus on late pre-clinical and/or clinical research

BHC-19 2019 Implementation research for maternal and child health 2-4 25 RIA

New or improved health service delivery interventions that strengthen maternal and child health;The scaling up and/or adapting of existing interventions to new contexts- Proposals should focus on implementation research for improving maternal and child healthduring the first '1000 days' from pregnancy until two years of age- Neither pre-clinical research nor clinical trials in the context of product development are withinthe scope of this call

16 avril 19

Call 1. Better Health and care, economic growth and sustainable health systems (suite)

1.3 Infectious diseases and improving global health (suite) Budg.Projet

BudgetTotal Type

02 Oct. 18 - 16 Apr. 19

02 Oct. 18 - 16 Apr. 19

1907/06/2018

1.4 Innovative health and care systems - Integration of care Budg.Projet

BudgetTotal Type

BHC-23 2018 Novel patient centered approaches for survivorship, palliation and/or end-of-life care 3-4 44 RIA

Demonstrate effectiveness and cost-effectiveness of new, improved or specifically adaptedpharmacological or non-pharmacological intervention to relieve symptoms and sufferingcaused by :- Life threatening non-communicable disease- Serious late and long term side effect of disease treatments in patients and survivor- Symptoms that occur at the end of lifeRandomized clinical trial/observational studies to be considered

BHC-26 2018 HTA research to support evidence-based healthcare 8-10 10 RIA

Develop new or improved approaches and framework to address- Specific types or groups of health technologies- Selected therapeutic areas- Use of real-world dataEffort should be directed at implementation of methodological work in the 3 areas

BHC-22 2019 Mental Health in the workplace 2-4 30 RIA

Develop and implement intervention(s) that employer/organization can take to promotegood mental health and prevent mental illness in the workplace- Co-morbidities to be addresses- Unpaid work and work at home include in the scope

BHC-25 2019 Demonstration pilots for implementation of Personalised Medicine in health care 15-20 60 RIA

Demonstrate the benefit for individuals as well as the implementability and economic viability of PM approaches in real life healthcare settingsDiseases with high burden to societyUse of big data and HPCEngage partners (region or cities) having adopted PM approaches already

18 avril 18

18 avril 18

02 Oct. 18 - 16 Apr. 19

02 Oct. 18 - 16 Apr. 19

Call 1. Better Health and care, economic growth and sustainable health systems (suite)

2007/06/2018

1.5 Decoding the role of the environment for health and well-being Budg.Projet

BudgetTotal Type

BHC-27 2018 New testing and screening methods to identify endocrine disrupting chemicals 4-6 52 RIAIncrease the quality and efficiency of existing methods to meet demanding and evolvingregulatory requirements worldwide research should improve and harmonise screening andtesting protocols/strategies and hazard/risk assessments with better and faster tools,methods or models, including high-throughput and in silicomethods- Focus should be on the most urgent regulatory needs (thyroid axis, female reproduction,non-genotoxic carcinogens and developmental neurotoxicity)- Potential work with JRC to be considered in the proposal

BHC-28 2019 The Human Exposome Project : a toolbox for assessing and addressing the impact of environment on health 8-12 50 RIA

Collect, combine and analyze large data sets offering new possibilities to understand thecontribution of environmental factors to the global health burden of common chronicdiseases identification of the most important environmental risk factors for thedevelopment of major NCDs across the life course (including in utero)- Well-designed retrospective epidemiological studies may be included- Creation of a prospective Europe-wide exposomics cohort and biobank, integratingbehavioural, socio economic factors and clinical records

- Coordination mechanism between the projects funded will be required and will be addedat the grant preparation stage

18 avril 18

16 avril 19

Call 1. Better Health and care, economic growth and sustainable health systems (suite)

2107/06/2018

Budg.Projet

BudgetTotal Type

DTH-03 2018 Adaptive smart working and living environment supporting active and healthy ageing 3-4 25 RIA

Proposals should develop and validate digitally enabled adaptive services and solutionsleading to smart work environments for older adultsProposals should be based on trans-disciplinary research, involving behavioural,sociological, psychological, medical and other relevant disciplines, including gender andcultural aspects.Development and integration of unobtrusive, adaptive solutions for age-friendly livingand working environmentsProposals should build on active user engagement in order to ensure the understandingof user needs

DTH -07 2018 Exploiting the full potential of in-silico medicine research for personaliseddiagnostic and therapies in cloud-based environments 10-15 35 RIA

Develop and validate software tools and devices for diagnostic or treatment based oncomputational modelling and simulation applied in biology and physiologyThe solutions should enable decision making for the choice of drugs, devices or otherbiomedical products, procedures, interventions, in vitro and in vivo diagnostics methodsand tools, or combined diagnostics and treatmentsThe teams are expected to use shared infrastructures and e-infrastructures, building onexisting capacity and expertise

DTH-08 2018 Prototyping a European interoperable Electronic Health Record (HER) exchange 4-6 30 IA

eHealth interoperability standardisation and harmonisationThis research and innovation action is expected to prototype on a larger scaleThe proposal shall demonstrate its ability to providing a cloud-based harmonised/standardised/interoperable health record

Call 2. Digital Transformation in Health and Care

24 avril 18

24 avril 18

24 avril 18

2207/06/2018

DTH-01 2019Big data and Artificial Intelligence for monitoring health status and quality of life after the cancer treatment 3-5 35 RIA

Improve quality of life after the cancer

Proposals should focus and deliver on how to better acquire, manage,

share, model, process and exploit big data to effectively monitor health

status of individual patients determining and monitoring the combined

effects of cancer treatment, environment, lifestyle and genetics on the

quality of life, enabling early identification of effects that can cause

development of new medical conditions and/or impair the quality of life

DTH-05 2019Large scale implementation of digital innovation for health and care in an ageing society 2-5 10 PPI

Specify, purchase and deploy ICT based solutions (made up of services and

ICT products to enable the provision of services) for active and healthy

ageing through a common supply and demand side dialogue

DTH-09 2019 Scaling up the univocal Identification of Medicinal products 4-6 19 IA

Enabling and fostering the use of a common EU medicinal Product

repository (ISO IDMP compliant) to fulfil the ePrescription/eDispensation in

a cross-border setting use case

Inclusion of a wide range of relevant stakeholders and experts including

inter alia National Competent Authorities, IT Integrators, producers of

ePrescribing, clinical record systems, SDOs

24 avril 19

24 avril 19

24 avril 19

Call 2. Digital Transformation in Health and Care (suite)

Budg.Projet

BudgetTotal Type

2307/06/2018

DTH-10 2019 Digital health and care services 5-6 22 PCP

Key challenges that could be addressed are patient empowerment, self-management, patient safety, patient involvement, chronic diseasemanagement, diagnosing, hospital logistics, skills and independent livingApplicable ICT domains e.g., telemedicine, mHealth, IoT, shared opensource IT-based platforms, etc. as will be defined in the market consultationprocess

DTH-11 2019 Large Scale pilots of personalised & outcome based integrated care 4-6 20 IA

Foster the large-scale pilots for deployment of trusted and personaliseddigital solutions dealing with Integrated Care to supporting and extendinghealthy and independent living for older individuals who are facingpermanently or temporarily reduced functionality and capabilities

14 nov 2018

24 avril 19

Call 2. Digital Transformation in Health and Care (Suite)

Budg.Projet

BudgetTotal Type

2407/06/2018

Call 3. Trusted digital solutions and Cybersecurity in Health and Care

Budg.Projet

BudgetTotal

Type

SU-TDS-02 2018Toolkit for assessing and reducing cyber risks in hospitals and care centres to protect privacy/data/infrastructures

3-5 35 RIA

Foster large-scale deployment of integrated digital solutions which will bring

improved quality of life

1) develop and deploy innovative and user-led digital solutions capable of

supporting and extending healthy and independent living for older individuals

who are facing permanently or temporarily reduced functionality and

capabilities

2) develop and deploy innovative and user-led solutions building on big data for

personalised risk detection, advanced health monitoring and early interventions

DT-TDS-01 2019Smart and healthy living at home Focus area "Digitising and transforming European Industry, Platforms and Pilots"

15-20 35 IA

Platforms for smart living at home that integrates a mix of advance ICT. 2 areas to

address :

- Digital solutions for sustaining healthy and independant living

- Personalised early risk detection

24 avril 18

14 Oct 18

2507/06/2018

Autres Appels concernant la Santé dans H2020

Ø EDCTP et Partenariat Public-Privé avec l’Industrie : IMI

Ø ERANET et JPI (joint programme initiatives)

Ø Défis sociétaux : SC2 « Food security and bioeconomy »SC5 « Climate action »SC6 « Inclusive, innovative and reflective societies »

Ø Pilier Excellence scientifique : FET Proactive et FET Flagship

Ø Pilier Primauté Industrielle : TIC et NMBP

2607/06/2018

Autres opportunités dans pilier 3

1. From functional ecosystems to healthy food

SFS-14

20182019

Personalized Nutrition (long term healthy and sustainable diets)Personalized Nutrition (innovative approaches for dietary assessment)

tbc tdc IA / RIA

H2020 Programme, SC2 Food, Call sustainable food security Project Budget

Total Budget Type

Innovating cities for sustainability and resilience Climate AdaptationSC5-14 2019 Visionary and integrated solutions to improve well-

being and health in cities 10 tbc IA

SC5-14 2019 Climate impacts in Europe (RIA)

a. Climate impact on health in Europe 5-7M€ 20 (a+b) RIA

H2020 SC5 Climate, call Greening the economy in line with theSustainable Development Goals (SDGs)

Project Budget

Total Budget Type

Innovation prizes, innovation policy

Prizen°20 2019

Horizon Prize for social Innovation in Europe1.Obesity in children2. Aging population

2M€ 2M€ 1 PRIZE

H2020 Programme, SC6 Europe in a changing world Project Budget

Total Budget Type

2707/06/2018

Platforms and Pilots Budg.Projet

BudgetTotal Type

DT-ICT-12 2019 Smart and healthy living at home 15-20 60 IA

A mix of advanced ICT ranging from biophotonics to robotics, from artificial

intelligence to big data and from IoT to smart wearables can address these

challenges. A platform for smart living at home should integrate these

technologies in an intelligent manner.

The pilots should build on open platforms, standardised ontologies, APIs and

results from IoT-based smart living environments, service robotics and smart

wearable & portable systems and clearly go beyond current state of the art

in terms of scale, the capabilities for personalisation, adaptation, and user

acceptance of the proposed solutions and services.

Two areas are of particular importance in this context:

• Intelligent and personalised digital solutions for sustaining and extending

healthy and independent living

• Personalised early risk detection and intervention

DT-ICT-13 2020 The smart hospital of the future TBD TBD IA

Plus d’infos: PCN ICT: ICI

23 Octobre 18

Pillier 2 : focus sur les Technologies de l’Information et de la Communication

28

OPEN INNOVATION HUBS Budg.

Projet

Budget

TotalType

DT-NMBP-02 2018 Open Innovation Hubs for Safety Testing of Medical Technologies for Health

(TRL4 to TRL7 )7-15M 75 IA

GOVERNANCE, SCIENCE-BASED RISK ASSESSMENT AND REGULATORY ASPECTS

NMBP-13 2018 Risk Governance of nanotechnology (TRL 4-6) 5 M 72 RIA

NMBP-14 2018 Nanoinformatics: from materials models to predictive toxicology and

ecotoxicology (TRL 4-6)6M 72 RIA

NMBP-15 2019 Safe by design, from science to regulation: metrics and main sectors (TRL 4-

6)5-6M 65 RIA

NMBP-16 2020 Safe by design, from science to regulation: behaviour of multi-component

nanomaterials TBD TBD RIA

NMBP-17 2020 Regulatory science for medical technology products TBD TBD RIA

MEDICAL TECHNOLOGY INNOVATIONS

NMBP-21 2020 Custom-made biological scaffolds for specific tissue regeneration and repair TBD TBD RIANMBP-22 2018 Osteo-articular tissues regeneration (TRL 3-5) 4-6 M 24 RIA

NMBP-15 2020 Next generation organ-on-chip TBD TBD RIA

Pillier 2: Nano .. NMBP

Plus d’infos: PCN NMP

29

Future and Emerging Technologies (FET)

Recherche collaborative, très risquée, interdisciplinarité, fort potentiel technologique sur moyen/long terme: incubateur d’idées innovantes

Roadmap-based researchOpen, light and agile

FET Open

Individual researchprojects

Early Ideas

FET Proactive

Open researchclusters

Incubation

FET Flagships

Common researchagendas

Large-Scale Initiatives

Future and Emerging Technologies

Exploring Developing Addressingnovel ideas topics & communities grand challenges

Un programme OUVERT

Un programme thématique

Une feuille de route sur 10 ans pour un domaine

d’intérêt majeur

3007/06/2018

FETPROACT-01-2018: emerging paradigms and communitiesAn innovation ecosystem around a new technological paradigm

§ Area 1 - Artificial organs, tissues, cells and sub-cellular structures (15M€)Integrative biology, bio engineering, replacement, control or repair of vital organfunctions, use in the development of personalized treatment, drugs or vaccine, etc..

§ Area 3 - Living technologies (20M€) Understanding of essential features of livingsystems such as physical autonomy, growth, interaction and enaction, adaptationand evolution, among others. Hybrid materials and systems with programmablefeatures of shape, structure, functionality and evolvability ; Work on ethicalimplications must be included

§ Budget/projet : 4 à 7M€ pour 5 ans§ Budget global : 88M€§ Deadline : 22 mars 2018

Future and Emerging Technologies (FET)

Infodays 2014/2015 - Point de Contact National ERC

1. Appels ERC 2018: calendrier

Starting Grants

(2-7 ans après PhD)Max. 1,5 M€ sur 5 ans

Deadline: 17 octobre 2017

Budget : 583 M€ (391)

Consolidator Grants

(7-12 ans après PhD)Max. 2 M€ sur 5 ans

Deadline: 15 février 2018

Budget : 553 M€(287)

Advanced Grants

Track-record 10 ansMax. 2,5M€ sur 5 ans

Deadline: 30 août 2018

Budget : 452 M€(194)

Proof of Concept

Aide à la valorisation d’idées émanant d’un projet ERC 150k€ réservés aux lauréats ERC

Deadlines: 16 janvier 2018 – 18 avril 2018 – 11 septembre 2018Budget: 20 M€ (130 bourses)

Synergy Grants

Equipe de 2 à 4 PIMax. 10M€ sur 6 ans

Deadline: 14 novembre 2017

Budget : 250 M€ (30)

Possibilité de financement supplémentaire

üChercheur venant d’un pays tiers, üAchat de gros équipement, üAccès grandes infrastructures

+ 0,5 M€ StG

+ 0,75 M€ CoG

+ 1 M€ AdG

+ 4 M€ SyG

33

Ø Programme du premier pilier “Excellence Scientifique” d’Horizon 2020,

bénéficiant d’un budget d’environ 13 milliards d’euros (17% de H2020)

Ø Financement de la recherche exploratoire

Ø Un seul critère : l’excellence

Ø Les chercheurs sont la clé de voûte :

• approche bottom-up (et non pas recherche ciblée)

• évaluation par les pairs

Ø Tous les domaines de la science et de la technologie

Ø Remboursement à 100% des coûts directs éligibles et des coûts indirects à

hauteur de 25% des coûts directs éligibles (hors sous-traitance)

1. ERC : Présentation générale

Starting/Consolidator Grant Advanced Grant

Taux de succès français Taux de succès européen

2. Résultats français : taux de succès

StG + CoG

% %

Horizon 2020

Marie Skłodowska-Curie Actions

MSCA - strategic programming approach

Ø Attract and retain research talentØ Develop state-of-the-art, innovative training schemes, consistent with the

highly competitive and increasingly inter-disciplinary requirements of researchand innovation

Ø Promote sustainable career development in research and innovationØ Focus on delivering new knowledge and skills, in line with the key driver

identified in the strategic programming approach

Ø Contribute to a strong partnership with MS via the co-funding mechanism

Key features of the MSCA partØ Open to all domains of research and innovation from basic research up to market

take-up and innovation services Ø Entirely bottom-upØ Participation of non-academic sector strongly encouraged, especially industry and

SMEsØ Mobility as the key requirement - funding on condition participants move from one

country to anotherØ Promotion of attractive working and employment conditionsØ Particular attention to gender balanceØ Budget 2014/2020 : 6 162 billion €

POUR VOUS AIDER :

07/06/2018

07/06/2018

Journée régionale d’information

Par exemple : 4 juillet 2017 – Journée d'information en Ile-de-France sur le Défi Santé d'Horizon 2020 co-organisée par Le réseau Entreprise Europe, Medicen Paris Region, Génopole, en association avec les P.C.N. Santé et P.M.E

Résultats du call 2018 Instrument PME phase 2 (cut off du 10 janvier) France: 9 retenus à l'audition /5 financés , Espagne 23/13, UK 7/2, DE 9/3, Italie 11/2, Finlande 8/5, NL 11/-Pour la France on notera que parmi les 5 projets sélectionnés 4 sont sur la thématiques Biologie-santé

07/06/2018

http://www.horizon2020.gouv.fr/07/06/2018

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