pyruvate

phosphoenolpyruvate

2,3

lactate4,5

oxaloacetate

6

7

8

formate

acetyl-CoA

910

14

15, 20

gluconeogenesis

CO2

glycolysis

2H+

2e-CO2 +22, 23, 24

Ljungdahl-Wood pathway

citrate

isocitrate

21

2-oxoglutarate

25

malate

succinyl-CoA

16

fumarate

18

19

succinate

1

menaquinone biosynthesis

heme biosynthesis

acetate

11a11b

acetaldehyde12

13

excretion

ethanol17

tryptophan26

11a; acetyl-CoA + AMP + PPi ATP + acetate + CoA11b; acetyl-CoA + H2O acetate + CoA + H+

No homolog; acetyl-CoA + Pi acetylphosphate + CoADhaf_3826; acetylphosphate + ADP acetate + ATP