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10.
040
9.1
61
7.4
95 7
.474
7.4
37 7
.432
7.4
27 7
.415
7.4
10 7
.398
7.3
93 6
.710
6.7
05 6
.693
6.6
88
4.5
98 4
.580
4.5
62
3.4
50 3
.447
3.4
30 3
.326
2.6
03 2
.511
2.5
06 2
.501
2.4
97 2
.492
2.4
19 1
.632
-0.0
01
3.00
1.01 0.99
6.02
1.98 1.02
2.21 3.07 2.94
10 8 6 4 2 0PPM
OTX015SOLVENT: dmsoF1 = 400.084564 MHz
MedKoo Biosciences www.medkoo.com [email protected]
MedKoo Biosciences Product Quality Control Data
www.medkoo.com | [email protected]
MedKoo Biosciences Product Quality Control Data
www.medkoo.com | [email protected]
MedKoo Biosciences Product Quality Control Data
www.medkoo.com | [email protected]
=====================================================================Acq. Operator : 1 Acq. Instrument : Instrument 1 Location : Vial 0Injection Date : 5/28/2015 1:37:49 PM Acq. Method : D:\CHEM32\Last changed : 5/28/2015 1:37:41 PM by 1 (modified after loading)Analysis Method : D:\CHEM32\Last changed : 5/28/2015 1:49:35 PM by 1 (modified after loading)Sample Info : A = ACN, B = 0.1% H3PO4/H2O] 10-95% A/B 3.5 min, 95% A/ B 4.5 min, 95-10% A/B 1 min, 10% A/B 1 min; Athena C18 (3 μm, 2.1 mm × 100 mm); Flow: 0.4 ml/min, T = 25 °C
min0 2 4 6 8
mAU
0
500
1000
1500
2000
2500
VWD1 A, Wavelength=254 nm (150528 HPLC-1.D)
4.4
17
5.2
06
===================================================================== Area Percent Report ===================================================================== Sorted By : SignalMultiplier: : 1.0000Dilution: : 1.0000Use Multiplier & Dilution Factor with ISTDs Signal 1: VWD1 A, Wavelength=254 nm Peak RetTime Type Width Area Height Area # [min] [min] mAU *s [mAU ] %----|-------|----|-------|----------|----------|--------| 1 4.417 BB 0.0771 1.26002e4 2610.67334 99.1269 2 5.206 BB 0.0624 110.98099 28.12309 0.8731 Totals : 1.27112e4 2638.79643 ===================================================================== *** End of Report ***
Sample Name: 150528 HPLC-1
Instrument 1 5/28/2015 1:49:38 PM 1 Page 1 of 1
Med
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MedKoo Biosciences Product Quality Control Data
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MedKoo Biosciences Product Quality Control Data
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MedKoo Biosciences Product Quality Control Data
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MS Spectrum
m/z0 200 400 600 800 1000
0
20
40
60
80
100
*MSD1 SPC, time=0.240:1.824 of D:\DATA\DDDCSYN\20150527\KR000023.D MM-ES+APCI, Pos, Scan, Frag: 70
Max: 19055
514
.0
88.
2
116
.2 1
15.2
87.
2
m/z0 200 400 600 800 1000
0
2.5
5
7.5
10
12.5
15
17.5
20
22.5
*MSD2 SPC, time=0.227:1.838 of D:\DATA\DDDCSYN\20150527\KR000023.D MM-ES+APCI, Neg, Scan, Frag: 70
Max: 4225
105
.1
528
.1
564
.2
85.
1
700
.2
493
.0 4
92.1
490
.1
Print of window 80: MS Spectrum
Instrument 1 5/27/2015 12:16:43 PM Page 1 of 1MedKoo Biosciences www.medkoo.com [email protected]
MedKoo Biosciences Product Quality Control Data
www.medkoo.com | [email protected]
MedKoo Biosciences Product Quality Control Data
www.medkoo.com | [email protected]
MedKoo Biosciences Product Quality Control Data
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OTX-015 分析报告
消旋化合物
Column : CHIRALPAK OJH
Column size : 0.46 cm I.D. ×25 cm L Injection : 10ul Mobile phase : CO2/MeOH=75/25(V/V) Flow rate : 2.0 ml/min Wave length : UV 254nm Temperature : 35 ℃
Daicel No. : OTX-015 Chromatogram
# tR Area Area% Height% NTP Resolution Symmetry Factor 1 5.173 35673754 46.588 61.854 3376 3.490 1.069 2 6.917 40899050 53.412 38.146 1836 N/A 1.016
5.173
6.917
0.0 1.0 2.0 3.0 4.0 5.0 6.0 7.0 8.0 9.0 Retention Time [min]
0
1000000
2000000
Inte
nsit
y [µ
V]
<Column Performance Report> M
edK
oo B
iosc
ienc
esw
ww
.med
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sale
s@m
edko
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MedKoo Biosciences Product Quality Control Data
www.medkoo.com | [email protected]
MedKoo Biosciences Product Quality Control Data
www.medkoo.com | [email protected]
MedKoo Biosciences Product Quality Control Data
www.medkoo.com | [email protected]
OTX-015 分析报告
制备后分析结果
< Chromatogram >
# tR Area Area% Height% NTP Resolution Symmetry Factor 1 4.985 31711652 99.962 99.972 3665 4.477 1.103 2 6.822 12117 0.038 0.028 3059 N/A 1.060
EE=99.9%
4.985
6.822
0.0 1.0 2.0 3.0 4.0 5.0 6.0 7.0 8.0 9.0 Retention Time [min]
0
1000000
2000000
Inte
nsit
y [µ
V]
Column : CHIRALPAK OJH
Column size : 0.46 cm I.D. ×25 cm L Injection : 10ul Mobile phase : CO2/MeOH=75/25(V/V) Flow rate : 2.0 ml/min Wave length : UV 254nm Temperature : 35 ℃
Daicel No. : OTX-015
<Column Performance Report>
OTX-015 Chiral Result
Med
Koo
Bio
scie
nces
ww
w.m
edko
o.co
msa
les@
med
koo.
com
MedKoo Biosciences Product Quality Control Data
www.medkoo.com | [email protected]
MedKoo Biosciences Product Quality Control Data
www.medkoo.com | [email protected]
MedKoo Biosciences Product Quality Control Data
www.medkoo.com | [email protected]
OTX-015 分析报告
制备后分析结果 Column : CHIRALPAK OJH
Column size : 0.46 cm I.D. ×25 cm L Injection : 10ul Mobile phase : CO2/MeOH=75/25(V/V) Flow rate : 2.0 ml/min Wave length : UV 254nm Temperature : 35 ℃
Daicel No. : OTX-015 < Chromatogram >
# tR Area Area% Height% NTP Resolution Symmetry Factor 1 5.027 136810 0.278 0.683 5150 3.782 1.019 2 6.813 49109036 99.722 99.317 1669 N/A 1.058
EE=99.4%
5.027
6.813
0.0 1.0 2.0 3.0 4.0 5.0 6.0 7.0 8.0 9.0 Retention Time [min]
0
1000000
2000000
Inte
nsit
y [µ
V]
<Column Performance Report> M
edK
oo B
iosc
ienc
esw
ww
.med
koo.
com
sale
s@m
edko
o.co
m
MedKoo Biosciences Product Quality Control Data
www.medkoo.com | [email protected]
MedKoo Biosciences Product Quality Control Data
www.medkoo.com | [email protected]
MedKoo Biosciences Product Quality Control Data
www.medkoo.com | [email protected]
