Centre d’Investigation Clinique (CIC) “Maladies Transmissibles: Histoire naturelle

et outils innovants pour le diagnostic, la prévention et le traitement”

Conseil Scientifique Elargi 8 Juillet 2016

16 CIC proposés

IPT retenu (en première position)

SELECTON DE L’IPT

Approche multidisciplinaire

et multisectorielle

Différents partenaires

Santé Recherche Industrie Pharmaceutique

OBJECTIF

Maladies transmissibles les plus prioritaires

Réduire l’impact économique, social, mortalité et morbidité

Projet 1 Projet 2

Projet 3 Projet 4

Core A Data Management

Core B Gestion des spécimens biologiques

Core C Gestion Administrative et financière Hé

patit

e

Tube

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ose

Leis

hman

iose

Comité Scientifique Comité de pilotage

ORGANISATION DU CIC

Service d’épidémiologie médicale Pr. Afif Ben Salah et ses collaborateurs

Laboratoire d’épidémiologie et génétique des virus hépatiques et entériques

Pr. Henda Triki et ses collaborateurs

Laboratoire d’épidémiologie moléculaire et pathologie expérimentale appliquée aux maladies infectieuses

Dr. Ikram Guizani et ses collaborateurs

Laboratoire de Transmission Contrôle et Immunobiologie des Infections

Pr. Ridha Barbouche et ses collaborateurs

Laboratoire d’épidémiologie et de microbiologie vétérinaire

Dr. Abdeljelil Ghram et ses collaborateurs

STRUCTURES IMPLIQUEES

Laboratoire de Microbiologie moléculaire, vaccinologie et développement biotechnologique

Dr. Helmi Merdessi et ses collaborateurs

Service de dermatologie / Unité de Trouble de la kératine

Pr. Mourad Mokni

Service de pneumologie / unité de Tuberculose Multirésistante et allergologie Pr. Fatma Tritar

Service de dermatologie de l’hôpital Houcine Bouzayén Gafsa Dr. Abdelhamid Kidar

Service de Gastroentérologie de Kasserine Dr. Ridha Marouani

Service de parasitologie de l’hôpital Farhat Hached Sousse Pr. Ag. Akila Fathalla Mili

Service ORL de l’EPS Charles Nicolle Pr. Mamia bensalah

Service Gastroentérologie La Rabta / STGE Dr. Nabil Ben Mami

service d’anatomie-pathologique de l’EPS Charles Nicolle

Pr. Soumaya Rammeh Rommani

Partenaires de l’Industrie Pharmaceutique

Représentants du secteur de la santé publique

Dr. Dhikrayet Gammara : responsable du programme national de la lutte contre la tuberculose

Dr. Zaher El Ahmadi: Directeur régional de la santé de Sidi Bouzid

Pr. Feriel Messaadi: Chef de laboratoire de santé publique du CHU Hedi chaker, Sfax

Dr. Abdelhamid Kidar: Dermatologie Hôpital Houcine Bouzaene de Gafsa

TDR Toolkit

Ethi

cs

GxP

Mod

ules

I an

d II

Mod

ules

III t

o VI

Target Population General Audience

Policy Makers Administrative managers Social Scientists Communication

Specialists

Implementers Preventive Programs

Managers

Researchers Medical Schools and

Laboratory

Training content

Promotion of good practices in research.

Translation of research products for health professionals and communities through IR.

II/ LEVELS 1. Institution/National 2. Regional and International

I/ STRATEGY

1. National level/ Institution

Medical Faculty of Tunis/ Institut Pasteur de Tunis

To promote the IR tool kit/ GCLP content. Target population: Under graduate, post- graduate training programs, PhDs…Post docs

Clinical investigation centers (CIC) RTC offers training on ethics and GCLP Target population: Training the trainers of the 4 CIC, cascade strategy.

Health actors at local and regional levels and young researchers

To promote a tradition of GHRP The Virtual University of Tunis

Progressively shift from face- to face training to a distant learning (MOOC)

2. Regional & International level

Coordination with EMRO to disseminate RTC courses e.g.: Cutaneous Leishmaniasis (CL)

The International Network of Pasteur Institutes (RIIP) to produce distant training content Other TDR RTCs

Other networks e.g. CL network, AUB, south-south…

National

CIC

IPT/ Medical School

Field actors

Training on site Training on line

Regional EMRO

American University of Beirut

South-South Network

International Network of RTCs

the International Network of Pasteur Institutes (RIIP)

Research program and cooperative agreement

WHO networks

Virtual University of Tunis

GCLP

ETHICS

CUTANEOUS LEISHMANIASIS

IR (WHO/TDR)

MEDIUM TERM

GHRP

ON LINE MSC DEGREE ON

GHRP/IR

LONG TERM

1st workshop WHO/TDR/EMRO small grants scheme at the RTC: Capacity Building in Tropical Disease Implementation Research Pasteur

Institute, Tunis, Tunisia,15 -17 June 2015

Target population: 20 participants from EMRO region Objective: to familiarize grantees with the concept and means of IR

2nd Workshop on Cutaneous Leishmaniasis (CL) for Clinical Researchers from the Eastern Mediterranean and African Region : 2 to 4 February 2016

Target population: 20 participants from EMRO (Morocco, Tunisia, Iran, Saudia Arabia, Afghanistan) /AFRO (Ethiopia, Burkina-Faso) /EURO (Turkey) regions working on Old World in cutaneous Leishmaniasis.

Website of RTC EMRO in Tunis

20

Faculty of Medicine of Tunis

Ali Mrabet (Trainer)

Jihène Bettaieb (Trainer)

Faculty of Social sciences

Fathia Saidi (Trainer)

Institut Pasteur de Tunis

Adel Gharbi ( Logistic support)

Afif Ben Salah (Scientific coordinator)

Aicha Boukthir (Pedagogic secretary and coordination)

Ali Bouattour (Trainer)

Dhafer Laouini (Trainer)

Hayet M’henni (Administrative Core of the Centre)

Hichem Ben Hassine (Trainer)

Ikram Guizani (Trainer)

Sadok Chlif (Trainer)

Wafa Kammoun (RTC coordinator )

Wissen Zid (Pedagogic Engineering)

Ministry of Health

Rym Hamza (Trainer)

Zied Laâtiri (Trainer)

Observatoire des Maladies Nouvelles et Emergentes

Nissaf Ben Alaya (Trainer)

(in alphabetical order)

Thank You