1 François Dabis

Recherche opérationnelle

- Pourquoi ?

- Quels objectifs ?

- Comment ?

AC12 - Recherche PTME - Nord & Sud

2 François Dabis

0

10

20

30

40

50

60

70

Percent female (%)

Sub-Saharan Africa

GLOBAL

Caribbean

Asia

E Europe & C Asia

Latin America

1990 ‘91 ‘92 ‘93 ‘94 ‘95 ‘96 ‘97 ‘98 ‘99 ‘00 ‘01 ‘02 ‘03 ‘04 ‘05 ‘06 2007

Year

% of HIV-Infected adults who are femaleby geographic location, 1990-2007

Source: UNAIDS/WHO Dec 2007

3 François Dabis

Despite Effective Regimens to Prevent MTCT, Globally Only 11% of Women Receive ARV Prophylaxis

8%12%

28%

16%

3%

14% 15%

37%

95%

2%

29%

77%

0%

25%

50%

75%

100%

India West &CentralAfrica

East &SouthAfrica

EasternAsia &Pacific

Central &South

America

Central &EasternEurope

%HIV+ women identified 2005 %HIV+ women given ARV 2005

Regions with95% of all MTCT

Interagency Task Team on PMTCT Report Card Feb 2007 UNICEF/WHO/UNAIDS

4 François Dabis

Accès aux services de PTME en Afrique sub-Saharienne, 2005

Guinea Bissau

Zimbabwe

Zambia

Central African Republic

Kenya

Côte d'Ivoire

Rwanda

SwazilandBurundi

Benin

Togo8080

Namibia7070

6060

5050

4040

3030

2020

1010

Uganda

Gabon

LesothoMozambique

Pourcentage de femmes ayant eu accès à une prophylaxie antirétrovirale pour la PTME

Tau

x d

e c

ouvert

ure

(%

)

5 François Dabis

Prenahtest ANRS 12127The public health impact of

couple-oriented counselling within low to medium HIV prevalence countries

Cameroon, Georgia, India, Santo Domingo

F. Dabis, P. Tchendjou

6 François Dabis

Prenahtest ANRS 12127 study design

Multicentric, international public health intervention study

Feasibility phase: define intervention components that are relevant and adapted to the local operational and socio-cultural contexts + evaluate the acceptability of the intervention

Intervention trial: evaluate the impact of couple-oriented post-test HIV counselling compared to standard post-test HIV counselling

Articulation quantitative - qualitative research methodologies

7 François Dabis

Recherche opérationnelle

- Pourquoi ?

- Quels objectifs ?

- Comment ?

AC12 - Recherche PTME - Nord & Sud